Parvoviridae Flashcards
Parvoviridae (meaning)
parvus-small
Subfamilies
Parvovirinae
Densovirinae
Parvovirinae genera
Proto-, Avi-, Amdo-, Boca-, Copi-, Tetra-,Erythro-, Dependo-parvovirus genus
Morphology
linear ssDNA – self-priming, hairpin ends
icosahedral capsid
non enveloped
Resistance
very strong
60°C, 60 min
pH 3-9
Biological properties
cellular polymerase - multiplication in dividing cells
complementation – adeno- or herpesvirus infected cells
hemagglutination
stenoxen
Antigenic properties
Very good Ag (long immunity) Cross reaction related viruses (mutants)
Diagnosis
isolation in dividing cells – intranuclear inclusion bodies
HA, IF, AGID
Serology: HAI, VN
Protoparvovirus genus (dis)
Porcine Parvovirus
Canine Parvovirus 2
Feline panleukopenia virus
Mink enteritis virus
Porcine parvovirus (clin signs)
Stillbirth, Mummification, Embryonic Death, Infertility
Canine Parvovirus 2
enteritis, myocarditis, exsiccosis
Aviparvovirus genus (dis and clin signs)
Chicken Parvovirus (stunting, diarrhoea, mortality)
Amdoparvovirus genus (dis and clin signs)
Aleutian mink disease virus
immunocomplex disease – hemorrhage, nephritis
Bocaparvovirus genus (A sp)
cattle
dog
Bocaparvovirus genus (dis)
Bovine parvovirus
Canine minute virus (canine parvovirus-1)