Polyclonal Antibodies Flashcards
1
Q
What makes up a polyclonal antibody?
A
Heterogenous B-cell lines that are sensitized to the different epitopes and produce different antibodies to the same antigen
2
Q
Sources of polyclonal antibodies
A
Different kinds of animals, humans
3
Q
IVIG definition
A
An IV blood product containing at least 90% of pooled IgG antibodies harvested from at least 1,000 patients
4
Q
Examples of IVIG
A
Gammagard S/D, Gammunex, Octagam
5
Q
IVIG is approved for…
A
…primary immunodeficiency, idiopathic thrombocytopenia purpura (ITP)
6
Q
Off-label uses for IVIG
A
Neonatal sepsis, autoimmune disease, acute infections
