Poliomyelitis Flashcards
What is poliomyelitis
Inflammation of the spinal cord
polio mainly affects children
under 5
how is polio transmitted?
person-to-person through fecal-oral route
Step 1 Polio transmission
Virus enters mouth
Step 2 Polio transmission
virus replicated in pharynx, GI, lymph, etc
Step 3 polio transmission
hematologic spread of virus to lymph and CNS
Step 4 polio transmission
virus spreads along nerve fibers
Step 5 polio transmission
destruction of motor neurons
How long can polio remain present in stool
up to 6 weeks
What does the poliomyelitis virus infect and affect
motor neurons in the spinal cord & Peripheral nerves; flaccid paralysis
Signs and symptoms of polio
fever, fatigue, headache, vomiting, stiffness of neck, pain in limbs
How many patients die due to diaphragm paralysis
5-10%
Types of Wild Poliomyelitis
Mahoney, Lansing, Sabin
Type 1 WPV
Mahoney; paralysis 1/200
only one left in circulation
Type 2 WPV
Lansing
eradicated in 199