Pleural Disease Flashcards
What is the normal pleural pressure? Why is it negative?
-5 cmH2O
It is negative due to the competing elastic recoils of the chest (outward) and lung (inward)
What determines the filtration coefficient of the pleura? When might it be increased?
“How leaky the pleura are”
May be increased in infection, inflammation, malignancy
What could cause an increase in Pulmonary capillary hydrostatic pressure leading to effusion?
LV failure
What could cause a decrease in pulmonary capillary oncotic pressure leading to effusion?
Cirrhosis
Malnutrition
Hypoalbuminemia
Nephrotic syndrome
What could cause a decrease in the pleural hydrostatic pressure leading to effusion?
Atelectasis
What are some physical exam findings of pleural effusion?
Dullness to percussion
Decreased breath sounds
Tactile fremitus
Egophony (e -> a change)
How might a pleural effusion be visualized on a CXR?
Blunting of the costophrenic angle
Meniscus sign
White out
Lateral decubitus position shows laying of fluid
What is a loculation? How is it treated?
Inflammatory pleural effusion due to infection that is well circumscribed because the area around it has fused and locked it in place.
Loculations require surgical intervention
How can you determine the difference between a pleural effusion and atelectasis on CXR?
You may see complete white out in both.
Look at the mediastinum. The mediastinum would shift towards atelectasis, but away from a pleural effusion
Where is the needle inserted in a thoracentesis?
OVER the rib (avoid the neurovascular bundle)
What are Light’s Criteria for determining if an effusion is exudate?
What is the one new “revised” criteria?
TPpl/TPserum greater than 0.5
LDHpl/LDHserum greater than 0.6
LDH greater than 200
Cholesterol(pl) greater than 45
What are the most common causes of transudative effusions?
Heart failure
Kidney failure
Liver failure
Atelectasis
What is an empyema? How is it different from a parapneumonic effusion?
Empyema - Infection in the pleural space
In a parapneumonic effusion, the infection is in the lung itself, which cause a pleural effusion. The pleura are not infection in a parapneumonic effusion
What can be determined by the pH of the pleural fluid?
Low pH may be seen with infection (empyema), malignancy, and esophageal rupture
How do you determine a hemothorax?
Blood in the pleural space
Pleural fluid hematocrit would need to be 0.5 or greater than peripheral hematocrit