Plasma Membrane-Fluid Mosaic Model Flashcards
By what is the Plasma Membrane-Fluid Mosaic Model determined?
Electron microscopy
What does the lipid bilayer of the cell membrane determine?
Permeability characteristics
Lipids of the bilayer composition
- Phospholipids
- Glycolipids
- Cholesterol
To describe having a polar/hydrophilic, and non-polar/hydrophobic portion
Amphipathic
Which bilayer composition is amphipathic?
Phospholipids
Portion of the phospholipids that face the inner and outer membrane surfaces and interact with the fluid environments
Polar/hydrophilic
Portion of the phospholipids that interact with one another to form the inner core of the bilayer
Hydrophobic/non-polar
The most abundant lipid component of the cell membrane
Phospholipids
Phospholipid function
Anchors proteins that have enzyme/transport functions
Where on the membrane are glycolipids present?
Outer face/leaflet
What does the extension of carbohydrates from the outer leaflet form part of?
Glycocalyx
Glycolipid functions
- Cell-to-cell communication
- Cell-to-matrix interaction
Where is cholesterol located?
Both surfaces of the cell
Cholesterol function
Maintains the cell’s structural integrity
To what is the bilayer essential?
- Membrane fluidity
- Activities such as endocytosis/exocytosis
Types of proteins
- Integral
- Peripheral
Proteins that are embedded into the phospholipid bilayer
Intergral
How far may integral proteins extend into the phospholipid bilayer?
Across the entire bilayer (transmembrane) or into the inner portion only
Integral protein characteristics
Glycoproteins with carbohydrate portion extending from the outer surface
Integral protein function
- Membrane receptors and transducers
- Transport or channel proteins
- Anchors the cytoskeletal elements
- Enzymes
- Carrier proteins
- Composition determines cell specificity
- Integrins
