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Histology > Cell Bio: Cytoskeleton > Flashcards

Cell Bio: Cytoskeleton Flashcards

1
Q

Cytoskeleton 3 major groups

A
  • Microtubules
  • Intermediate filaments
  • Microfilaments
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2
Q

Largest of the cytoskeletal elements

A

Microtubules

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3
Q

What are microtubules made of?

A

A protein called tubulin

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4
Q

Microtubule functions

A
  • Maintenance of cell shape
  • Macromolecule transport within the cytosol
  • Granule transport & movement of chromosomes during mitosis
  • Spindle filaments of mitotic spindle
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5
Q

Microtubule locations

A
  • Centrioles
  • Cilia
  • Flagella
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6
Q

A heterogenous group of filaments that are found surrounding the nucleus and forming a network of filaments inside the cytoplasm

A

Intermediate filaments

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7
Q

Intermediate filaments are divided into different groups which have a specific:

A

Distribution in various cell types

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8
Q

Cytokeratins

A

Epithelium

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9
Q

Desmin

A

Muscle

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10
Q

Vimentin

A

Cells derived from mesoderm:
- Fibroblasts
- Chondroblasts
- Macrophages

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11
Q

Glial fibrillary acid protein

A

Glial/support cells in the nervous system

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12
Q

Neurofilaments

A

Neurons

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13
Q

Microfilaments are composed of

A

The protein actin

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14
Q

Actin filaments are associated with proteins to form what?

A

A layer beneath the cell membrane

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15
Q

The proteins associated with the actin filaments are also associated with membrane activities such as

A
  • Exocytosis
  • Endocytosis
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16
Q

What do actin filaments form?

A

Rigid bundles

17
Q

What do the rigid bundles formed by actin filaments do?

A

Protrude into microvilli

Histology (12 decks)

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