Cell Bio: Membranous Organells Flashcards

1
Q

Found in every cell, but the amount may differ depending on the major function of the cell

A

Membranous organelles

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2
Q

Seen in an electron micrograph as a membrane-lined sac

A

Rough Endoplasmic Reticulum (RER)

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3
Q

What is the RER’s outer surface covered with?

A

Ribosomes

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4
Q

What is the RER’s interior region called?

A

Cisterna

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5
Q

What is the membrane of the RER continuous with?

A

Outer membrane that surrounds the nucleus

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6
Q

The RER is present in all cells but where are they particularly abundant?

A

In cells specializing in protein secretion

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7
Q

Proteins synthesized by the RER

A
  • Secretory proteins
  • Enzymes of the lysosome
  • Proteins that will become part of the membrane proteins of the:
    1. ER
    2. Golgi apparatus
    3. Lysosomes
    4. Plasma membranes
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8
Q

Where does post-translational modifications of proteins occur?

A

Cisternae of the RER

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9
Q

Examples of post-translational modifications of proteins

A
  • Folding
  • Association of protein subunits
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10
Q

Where do the vesicles of the newly synthesized proteins move to?

A

Membrane of the Golgi

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11
Q

What does the golgi do to the newly synthesized protein?

A

Further modifies

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12
Q

Ribosomes are small particles composed of what?

A

Ribosomal RNA

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13
Q

Some ribosomes are attached to what?

A

RER

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14
Q

Ribosomes that aren’t attached to the RER

A

Free ribosomes

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15
Q

What are free ribosomes responsible for?

A

Formation of proteins used within the cell (various cellular enzymes)

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16
Q

Irregular network of smooth channels that appear to be tubular

A

Smooth Endoplasmic Reticulum (SER)

17
Q

What is SER responsible for?

A

Synthesis of membrane phospholipids (as well as cholesterol and triglycerides)

18
Q

SER are particularly prominent in cells that do what?

A

Synthesize steroid hormones

19
Q

SER are found in these type of cells that are exposed to certain drugs

A

Hepatocytes

20
Q

Enzymes involved in which action is attached to the SER?

A

Detoxification

21
Q

What is the SER called in muscle cells?

A

Sarcoplasmic reticulum

22
Q

What is the sarcoplasmic reticulum involved in?

A

Storage of calcium (necessary for the initiation of muscle contraction)

23
Q

Appear as parallel stack of plate-like membrane compartments

A

Golgi apparatus

24
Q

Organelle that appears as parallel stack of plate-like membrane compartments

A

Golgi apparatus

25
Q

Golgi function

A

Processing of proteins that are synthesized on the RER

26
Q

How do the proteins synthesized on the RER reach the golgi?

A

Vesicles containing secretory products from the RER travel to the golgi

27
Q

Where does the addition of carbohydrates to certain AAs (forming glycoproteins) occur?

A

Golgi

28
Q

What are the proteins modified by the golgi packaged into?

A

Vesicles or granules

29
Q

Where are the proteins modified by the golgi transported?

A

Out of the cell (via a signal)

30
Q

What is the plasma membrane constantly doing?

A

Changing

31
Q

Some vesicles that leave the golgi complex are loaded with digestive enzymes and become incorporated into what?

A

Lysosomes

32
Q

Membrane enclosed vesicles that contain digestive enzymes

A

Lysosomes

33
Q

What do lysosomes contain a large number of?

A

Hydrolases