Plasma cell membrane Flashcards

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1
Q

What is the plasma membrane function ?

A
  • Act as a barrier between the cell and the environment – they control what moves into and out of the cell. The plasma membrane is partially permeable so it lets some substance through but not others.
  • Cell recognition – glycoproteins on the plasma membrane act as antigens, telling the immune system that the cell is not a foreign pathogen.
  • Cell communication – receptors on the plasma membrane bind to hormones or other chemicals released by other cells.
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2
Q

What are the functions of intracellular membranes ? Facc

A
  • Compartmentalises the cell – internal membranes act as a barrier between organelles and the cytoplasm, allowing them to function more efficiently by keeping enzymes and molecules in one place.
  • Form vesicles to transport substances around the cell.
  • Control what moves into and out of organelles – intracellular membranes are partially permeable.
  • Act as the site of chemical reactions – for example, thylakoid membranes inside chloroplasts are where photosynthetic reactions take place.
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3
Q

What is the fluid mosaic model ?

A

Fluid mosaic model
* The structure of the plasma membrane is made up of a bilayer of phospholipids with proteins and cholesterol interspersed throughout the structure.
* The fluid mosaic model is used to describe the arrangement of molecules in the membrane - ‘fluid’ because the phospholipids are constantly moving around and ‘mosaic’ because protein molecules are scattered throughout the phospholipids like tiles in a mosaic

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4
Q

What are the components of the cell membrane ?

A
  • Phospholipids
  • Glycoproteins
  • Glycolipids
  • Cholesterol
  • Intrinsic proteins
  • Extrinsic proteins
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5
Q

What is a phospholipid ?

A
  • Phospholipids ( creates a bilayer) : consist of a hydrophilic head group which faces the intracellular / extracellular fluid and two hydrophobic tails which point towards each other, away from water. They are the main component of the plasma membrane and form a barrier to anything which is not lipid-soluble (such as ions and glucose).
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6
Q

**What is a Glycoprotein ? **

A
  • These are proteins with sugar molecules attached. They act as recognition sites and antigens - antigens are like little ‘flags’ on the surface of our cells which allows our body to detect which cells are our own and which cells are foreign.
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7
Q

What is a Glycolipid ?

A
  • These are phospholipids with sugar molecules attached. They have a similar function to glycoproteins - they also act as recognition sites and antigens. They also increase membrane stability by forming hydrogen bonds with water molecules.
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8
Q

What is cholestrol?

A
  • Cholesterol: cholesterol is a lipid which slots in between the phospholipid tails, pushing them closer together. It regulates the stability and fluidity of the plasma membrane.
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9
Q

What are Intrinsic proteins ?

A
  • Intrinsic proteins: these are proteins which span both bilayers of the plasma membrane. They act as channels or carrier proteins to transport water-soluble molecules.
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10
Q

What are Extrinsic proteins ?

A
  • These are proteins which are found on the surface of the plasma membrane. They usually function as enzymes and catalyse chemical reactions inside the cell.
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11
Q

What are the factors affecting the membrane permeability ?

A
  • Temperature
  • PH
  • Solvent concentration
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12
Q

**Explain solvent concentration **

A

-The more easily the phospholipid bilayer is dissolved, the more permeable the membrane is.
- Solvent concentration can be controlled by using the same solvent at the same concentration for each trial.

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13
Q

Explain temperature

A

-Higher temperatures increase the fluidity of the membrane, increasing its permeability.
- Using a water bath can help keep temperature constant.

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14
Q

Explain PH

A

-pH affects the protein structure in the cell membrane.
-Buffer solutions can be used to control the pH.

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15
Q

**What’s is cell signalling ? **

A
  • When cells communicate to each other
  • Cell signalling starts when one cell releases a messanger molecule this molecule travels to another cell and is detected by the membrane and it binds to a receptor, the binding triggers a change in the cell.
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16
Q

What are membrane-bound receptors ?

A
  • Proteins that act as receptors for messenger molecules
  • They have a specific shape so they can bind to them
  • A cell that responds to a particular messanger molecule is called a target cell.
17
Q

What are the role of drugs ?

A
  • Many drugs work by binding to the receptor cells to either trigger a response or block a receptor and prevent it from working.
18
Q

What is Diffusion ?

A
  • Diffusion is the net movemnet of particles from a region of higher concentration to a region of lower concentration.
  • At equilbrium no net movement diffusion has stoppped
  • Passive process - doesnt require metabolic energy
18
Q

Factors that affect diffusion

A
  • concentration gradient
  • thickness
  • temperature
  • surface area