Pituitary Physiology Flashcards

1
Q

what is in the cavernous sinus

A

cranial nerves (3,4,5,6) and the internal carotid artery

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2
Q

what tissues does lactin act on

A

mammary glands

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3
Q

what pituitary hormones act on non endocrine tissues directly

A

growth hormone and prolactin

ADH and oxytocin

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4
Q

what carries anterior pituitary hormones

A

blood stream

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5
Q

what carries posterior pituitary hormones

A

neurones

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6
Q

what is vasopressin

A

ADH

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7
Q

what is the response from the hypothalamus in response to cold exposure

A
released thyrotropin releasing hormone 
-
acts on anterior pituitary 
- 
releases thyrotropin 
- 
acts on thyroid 
-
release thyroxine
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8
Q

what organs does testosterone act on

A
muscle 
bone 
libido 
penis 
hair follicles
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9
Q

what organs does estrogen and progesterone act on

A

bone
fat (peripheral)
vagina
heart and liver

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10
Q

what hormone from the pituitary acts on the ovaries to make them secrete estrogen and progesterone

A

FSH

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11
Q

what hormone from the pituitary acts on the testes to make them secrete testosterone

A

LH

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12
Q

what hormone stimulates the pituitary to release LH and FSH

A

gonadotrophin releasing hormone

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13
Q

what stimulates the pituitary gland to produce ACTH

A

corticotrophin releasing hormone

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14
Q

what is released from the posterior pituitary

A

OXT, ADH

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15
Q

what does ACTH stimulate the production of

A

cortisol

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16
Q

what does TRH stimulate the production of

A

TSH

17
Q

what does GnRH stimulate the production of

A

LH/FSH

18
Q

what does GHRH stimulate the production of

A

GH

19
Q

what does dopamine inhibit the production of

A

PRL

20
Q

what does CRH stimulate the production of

A

ACTH

21
Q

what does TSH stimulate the production of

A

thyroxine

22
Q

what does LH/FSH stimulate the production of

A

E2/testosterone

23
Q

what is the peripheral ‘paired hormone’ for GH

A

IGF-1

24
Q

what can a tumour in the pituitary gland locally compress

A

structures in the cavernous sinus (cranial nerves, carotid artery)
cranial nerves
optic chiasma
sphenoid sinus

25
Q

what test should be used if there is too much of a hormone

A

a suppression test- try and suppress the hormone thats in excess

26
Q

what test should be done if there is too little of a hormone

A

test to stimulate the production of the hormone (see if it is produced in normal way)

27
Q

name 3 dynamic pituitary stimulation tests

A

synacthen (should raise cortisol)
insulin stress test/ prolonged glucagon test (cortisol and GH should be raised)
water deprivation tests (ADH should be stimulated, urine should increase in concentration)