Anatomy of the Pituitary gland (and strap muscles and adrenal gland) Flashcards
name the endocrine glands in the cranial cavity
hypothalamus and pituritary (hypophysis)
name the endocrine glands in the neck
4 parathyroid glands and thyroid glands
name the endocrine glands in the abdomen
2 adrenal (suprarena)l glands and the pancreas
name the endocrine glands in the pelvis
female- ovaries
male- testes
what is the diencephalon
= thalamus + hypothalamus
forms the central core of the cerebellum with connections to the right and left cerebral hemispheres and the midbrain
what connects the hypothalamus to the pituitary gland
infundibulum (pituitary stalk)
what are the parts of the pituitary gland
anterior and posterior pituitary
what part of pituitary connects to the infundibulum
the posterior
what is the difference between the anterior and posterior pituitary
anterior is glandular
posterior is neural
(result of embryological development)
what is the adenohypophysis
the anterior pituitary
what is the anterior pituitary made up of
pars distalis, pars tuberalis and pars intermedia
what is the role of the anterior pituitary
synthesis and release of most pituitary hormones (GH, TSH, ACTH, FSH, LH, PRL)
where would you get an adenoma in your pituitary gland
in the anterior lobe as glandular
what is the nuerohypophysis
posterior lobe of pituitary gland
what makes up the posterior pituitary
pars nervosa
what is the posterior pituitary an extension of
the brain
what is the role of the posterior pituitary
releases ADH and OT (oxytocin)
where is the pituitary gland located in the skull
midline structure- in the pituitary fossa of the sphenoid bone
pituitary fossa lies within the sella tucica (turkish saddle)
where does the pituitary gland lie in relation to nerves
immediately inferior to the optic chiasm (where optic nerves come together)
what passes posteriorly from the optic chiasm
the left and right optic tracts
what happens to the axons of the optic nerve in the optic tracts
synapse with hypothalamus and then pass via the optic radiation to the visual cortex in the occipital lobe
what are the parts of the retina
nasal retina- peripheral vision
temporal retina- inner vision
what does the retina contain
photoreceptors: rods and cones
where is the optic canal and what goes through it
in sphenoid bone
optic nerve
where do the signals from the different sides of the retina separate into the correct optic tract
optic chiasm
what is the early clinical effect of a pituitary tumour on the visual pathway
initial midline compression of the optic chiasm
disrupts the transmission of action potentials from the nasal retina bilaterally
loses ability to see temporal visual field
=bitemporal hemianopia (loss of peripheral vision)
what are the approaches to the pituitary fossa
transcranial- subfrontal (under the frontal lobe)
transsphenoidal approach (via nasal cavities and sphenoidsinus- requires surgical fracture of nasal septum and the floor and roof of the sphenoid sinuses)
what is the roof of the nasal cavity
the cribiform plate of the ethmoid bone
what are the parts of the nasal septum
vomer and perpendicular plate of the ethmoid bone (superior part)
what are the paranasal sinuses
air filled spaces within the bones surrounding the nasal cavities
what are the four types of paranasal sinuses
frontal bone- frontal sinuses
maxillae- maxillary sinuses
ethmoid bone- ethmoidal aircells
sphenoid bone- sphenoid sinuses
what lines paranasal sinuses
mucous secreting respiratory mucosa
what is the purpose of the paranasal sinuses
make mucous, drain it into the nasal cavities through ostia (singular= ostium- bony drainage hole)
reduce the weight of the skull
add resonance to the voice
where are the right and left eithmoid air cells found (3 groups)
between the nasal cavity and the orbit
where are the sphenoid sinuses
within the body of the sphenoid bone- sometimes connect midline
where are the maxillary sinuses
one in each maxilla
what type of le fort fractures provides good surgical access to the pituitary gland
le fort 1
what is the entire cranial cavity lined with
sura matter
what is the tenrorium cerebelli
sheet of dura matter which tents over the cerebellum within the posterior cranial fossa with a central gap to permit the brainstem to pass through
what is the diaphragm sellae
a tough sheet of dura matter forming a roof (diaphragm) over the pituitary fossa
what are the dural venous sinuses
venous channels within the dura matter that drain most of the venous blood from the cranial cavity (and brain) into the the jugular veins
what does the anterior intercavernous sinus do
connects the right and left cavernous sinuses anterior to the pituitary gland
where do the dural venous sinuses drain into
the internal jugular veins at the jugular foraminae in the floor of the posterior cranial fossa
what sinuses surround the pituitary gland
cavernous and intercavernous sinuses
what passes through the cavernous sinuses
internal carotid arteries
what is the ophthalmic artery and how does it enter the orbit
branch of the internal carotid artery
enters the orbit via the optic canal
what makes the lateral wall of the cavernous sinuses
dura matter
where is the diaphragm sellae in relation to the pituitary gland
pituitary gland is inferior to the diaphragm sellae
why do you not attempt surgery in the lateral side of the head
due to tortuous path of internal carotid in the cavernous sinus
what is the function of the optic chiasm
conducrs AP’s bilaterally from the nasal retinae
what is the function of the oculomotor nerve
motor to muscles that move the eyeball (globe)
parasympathetic to the sphincter muscle of the iris
what is the functional deficit of the oculomotor nerve
at risk in pituitary gland surgery
problems with eye movements
a dilated pupil
what does the trochlear nerve do
motor to one muscle that moves the globe
what is the function deficit of the trochlear nerve
at risk in pituitary gland surgery
problems looking inferiorly and laterally
what is the function of the trigeminal nerve
sensory to most of the face
motor to the muscle of mastication
what is the function deficit of the trigeminal nerve
at risk in pituitary gland surgery
sensory symptoms on the face
difficulty chewing
what is the function of the abducent nerve
motor to one muscle that moves the globe
what is the function deficit of the abducent nerve
at risk in pituitary gland surgery
problems abducting the eye
what is the function of the cavernous sinus
drain venous blood
what is the function deficit of the cavernous sinus
at risk in pituitary gland surgery
venous haemorrhage
what is the function of the internal carotid artery
supplies arterial blood to brain and orbit (inc globe)
what is the function deficit of the carotid artery
at risk in pituitary gland surgery
catastrophic haemorrhage
what is the function of the dura matter
protects the structures of the cranial cavity
what is the functional deficit of the dura matter
at risk in pituitary gland surgery
cerebrospinal fluid (CSF) leak
what are the three branches of the trigeminal cranial nerve
opthalmic, maxillary, madibular
which lobe of the brain lies in the middle cranial fossa
pituitary gland
which cranial nerves lies close to the internal carotid artery in the cavernous sinus
abducent nerve
what foramen do the branches of the trigeminal nerve go through
opthalmic- superior optic sinus
maxillary- foramen rotundum
mandibular- foramen ovale
how do you remeber the names of the strap muscles
look at where they attach to and from (sternohyoid, thyrohyoid- except omohyoid)
what innervates the strap muscles
all innervates by ansa cervicalis (anterior rami of C1-3) except thryohyoid which is hypoglossal
what is the function of somatostatin and where else is it released in the body
In the hypothalamus, it regulates the secretion of hormones coming from the pituitary gland
In the pancreas, somatostatin inhibits the secretion of pancreatic hormones, including glucagon and insulin
describe the blood supply to the pancreas
gastroduodenal- superior pancreatic- anastomosis- inferior pancreatic- superior mesenteric
splenic artery- dorsal pancreatic
where are your adrenal glands
retroperitonium, superior to kidneys
what separates your kidneys and adrenal glands
fascial septum
what are the parts of the adrenal glands and their functions
adrenal cortex- glucocorticoids, mineralocorticoids, androgens
adrenal medulla- adrenaline, noradrenaline
what is the difference between adrenaline and noradrenaline
adrenaline- acts on beta and alpha: increased blood sugar levels
increased heart rate
increased contractility
relaxation of smooth muscle in the airways
noradrenaline: only acts on alpha (found in arteries): increased blood sugar levels increased heart rate increased contractility vasoconstriction (increased blood pressure)
describe the blood supply to the adrenal gland
inferior (branch of renal), middle and superior (branches of aorta) suprarenal arteries
what is the venous drainage of the blood supply
suprarenal vein, renal vein, IVC
what do the different parts of the pituitary glands secrete
anterior- ACTH, FSH, GH, LH, prolactin, TSH
intermediate- MSH
posterior- ADH, oxytoxcin
what do hypothalmic hormones produce
releasing hormones (stimulate pituitary) release inhibitory hormones
what transports hypothalmic hormones to the end capillary bed in the anterior pituitary gland
hypophyseal portal system
what are the embryological origins of the parts of the pituitary gland
anterior- upgrowth of oral ectoderm (rathke’s pouch)
posterior - downgroth of diencephalon
where is the carvernous sinus
bilaterally to the sella turcica and extends from the superior orbital fissure anteriorly to the petrous part of the temporal bone posteriorly
what artery can cause haemorrhage in the middle fossa of the brain
internal carotid
what nerves are in the carvernous sinus
3,4 and 6th cranial nerve