Pilocystic Astrocytoma Flashcards
1
Q
definition, age range
A
slow growing, well circum tumor in kids
2
Q
incidence by location
A
10% of cerebral tumors, 85% of cerebellar tumors
3
Q
age/sex distribution
A
20 yo, equal sex
4
Q
most common locations
A
cerebellum, brain stem, thalamus, basal ganglia, optic chiasm, optic nerve
5
Q
signs/symptoms
A
h/n/v clumsiness
near the optic tract - visual disturbances
thalamic tumors - hemiparesis (internal capsule impingement)
6
Q
imaging
A
well circum, contrast enhancing, cystic
7
Q
histology
A
hair like cytoplasmic processes, biphasic architecture with packed cells and loose cells
Rosenthal fibers/eosinophilic granular bodies - correlate with lower grade
8
Q
genetics
A
NF1, deletions of 17q
