Ependymoma Flashcards
1
Q
grade
A
2 or 3
2
Q
age/sex
A
equal among ages (higher on the differential in children) equal sex
3
Q
location
A
intracranial and posterior fossa account for most
adults - supratentorial (although adults account for most spinal cord)
children - posterior fossa
4
Q
signs/symptoms
A
seizures focal deficits (supratentorial)
Posterior fossa - ataxia, visual disturbances, h/n/v
spinal - motor and sensory symptoms
5
Q
imaging
A
hemorrhage, calcification, cyst or syrinx
6
Q
gross path
A
soft, tan tumors, well circumscribed
7
Q
histology
A
monomorphic nuclei, long fibrillar cytoplasmic processes, pseudorosettes (clusters of anuclear areas around blood vessels)
8
Q
genetics
A
monosomy 22
22q problems (esp. spinal cord tumors)
NF2 (spinal cord)
9
Q
prognosis
A
better for supratentorial tumors (adults do better)
