Neurofibroma Flashcards
1
Q
definition
A
schwann cells and fibroblasts
2
Q
incidence
A
usually single and sporadic; if multiple, think NF1
3
Q
location
A
1) cutaneous
2) circumscribed in peripheral nerves
3) plexiform (multinodular)
4) diffuse soft tissue tumors
4
Q
signs/symptoms
A
not painful, slow growing masses
5
Q
gross path
A
1) gray glistening cut surface
2) fusiform, gelatinous
3) multinodular
4) soft, gray, glistening
6
Q
genetics
A
NF1 (17q12)
7
Q
histology
A
rare mitotic figures, schwann cells and fibroblasts
8
Q
prognosis
A
usually good, unless it’s the diffuse form; plexiform tumors may progress in grade
