Oligodendroglioma Flashcards
1
Q
types of cells and usual location
A
oligodendrocytes in the cerebrum
2
Q
grade
A
2 or 3
3
Q
age/sex
A
40-60; 1:1/2:1
4
Q
signs/symptoms
A
seizures/headaches
5
Q
imaging
A
white matter, with calcifications
6
Q
gross path
A
grayish-pink, soft or gelatinous
7
Q
histology
A
fried egg cells/honeycomb
grade 2 has no mitotic figures
grade 3 has some, along with tumor necrosis and microvascular proliferation
8
Q
genetics
A
LOH on 19q and 1p
isocitrate dehydrogenase
9
Q
what is the prognosis for genetic mutations
A
those with deletions tend to do better
