Picornaviridae Flashcards
picorna means
picoRNA
pico: little
morphology
+ssRNA, icosahedral capsid, naked
resistence
(naked) good
cardio, rhino - weaker
replication
baltimore IV - short replication cycle: very contagious!!
(+ssRNA is very similar to mRNA)
host specificity
stenoxen except Aphtho
antigenic properties
good(long lasting ab’s), no cross reactions
name the 11 genera we will focus on
Entero-, Tescho-, Hepato-, Avihepato-, Tremo-, Cardio-,
Aphtho-, Erbo-, Parecho-, Kobuvirus genus
enterovirus genus affects which animals(mainly)
swine
bovine
human (monkey)
enterovirus genus most important disease; symptoms
ND! swine vesicular disease (SVD)
- porcine picornavirus 9
- spreads from stomach->intestines where it multiplicates, then enter blood to spread everywhere!
teschovirus genus: disease, symptoms
(swine)
porcine teschovirus 1: teschen/talfan disease
- paralysis: poliomyelitis aka polio causes muscle weakness leading to the inability to move
tremovirus genus:
avian encephalomyelitis
- chicken: epidemic tremor (constant shaking leading to paralysis and death, affects the brain!)
hepatovirus genus:
hepatitis A: human icterus
- acute, food born
(simian hepatitis A)
cardiovirus genus: disease, spread
encephalomyocarditis disease
- euryxen: wide host range from rodents (swine, horse, human, elephants)
aphtovirus genus: disease, symptoms, spread
ND!foot and mouth disease
- (aphtha - vesicles) oral cavity, hoof, enteric mucosa
- euryxen: RU, swine, human
erbovirus genus: disease and symptoms
Equine rhinitis B (erb-ovirus)
- upper respiratory problems
