Papillomaviridae

Question 1

papilloma means

Answer 1

(Papilla – wart, oma – tumor)

Benign tumours can change to malignant carcinomas

Question 2

papillomatosis is…

Answer 2

papillary projections of the epidermis (warts)

Question 3

papillomatosis affects which animals

Answer 3

canine
humans
bovine
horse

Question 4

Equine papillomatosis

Answer 4

bovine serotypes can cause horse sacaroids on head and nose, transmission by bit, twitch

Question 5

canine papillomatosis

Answer 5

epulis - in oral mucosa

Question 6

human papillomatosis 1-63

Answer 6

skin papillomas - verruca vulgaris (common papillomas)
genital papillomas
- juvenile laryngeal cacinomas
- cervical intraepithelial neoplasia
- vulval, penile carcinomas
(carcinoma: cancer in epithelial tissue of skin)

Question 7

bovine papillomatosis 1-13

Answer 7

on neck and back body

Question 8

latency of papilloma virus

Answer 8

episomal latency

- using genetic episomes during latency

Question 9

other animals that can be infected

Answer 9

sheep, roe deer, elephant, elk, possum, rabbit, turtle, parrot

Question 10

morphology

Answer 10

non-enveloped, icosahedral capsid, circular dsDNA=more resistant, strong resistance

Question 11

replication

Answer 11

baltimore 1
replication in the nucleus by cellular transcriptase
virion release by cell lysis

Question 12

transmission

Answer 12

contact/sex

Question 13

propegation

Answer 13

in keratinized cells (skin), not in other tissues!

Question 14

antigenic properties

Answer 14

good antigens (hide from immune system)

Question 15

diagnosis

Answer 15

warts appear