Hepadnaviridae Flashcards

1
Q

hepadna meaning

A

(hepa-dna)
hepar - liver
DNA

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2
Q

morphology

A

circular dsDNA, icosahedral, enveloped

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3
Q

resistance

A

(enveloped) weak

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4
Q

replication

A

baltimore VI! replication using reverse transcriptase in cytoplasm, then when DNA it enters nucleus

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5
Q

transmission

A

blood, sexual, close contact

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6
Q

antigenic properties

A

HBsAG - australia antigen, serves a protective role

HBcAg, HBeAg: viral proteins making it an infectious disease

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7
Q

the 2 genuses of hepadnaviridae family

A

orthohepadnavirus

Avihepadnavirus

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8
Q

orthohepadnavirus: its (3) virus species

A

Hepatitis B

(human hepatitis B aka serum hepatitis can lead to the development of hepatocarcinoma
(woodchuck hepatitis, ground squirrel hepatitis)

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9
Q

Avihepadnavirus: its virus species

A

Duck hepatitis B in the far east

stork, crane, heron, wild goose hepatitis B viruses

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10
Q

type of infection, symptoms

A

chronic, persistance infections which infect the liver ->-> liver failure

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