Asfarviridae

Question 1

asfar meaning

Answer 1

ASF - african swine fever

Question 2

morphology

Answer 2

linear dsDNA, icosahedral, enveloped

Question 3

resistance

Answer 3

(enveloped)weak (survive in pork meat for months - smuggling)

Question 4

replication

Answer 4

Baltimore 1, replication in CYTOPLASM! using viral enzymes

Question 5

transmission

Answer 5

• contact(europe)

- arbo (arthropods) (africa, too hot/dry to spread by contact)

Question 6

reservoir

Answer 6

africa, wart-hog

Question 7

antigenic properties

Answer 7

hidden antigen - antibody cannot neutralize!
- no vaccine
- persisting infections with clinical symptoms
(neutralizing ab’s emerge in late stage of infection)

Question 8

asfarvirus genus: disease

Answer 8

african swine fever

- high mortility and morbidity(having a disease) rate

Question 9

symptoms of ASF: acute vs. chronic

Answer 9

acute: fever, haemorrhage of skin + organs
chronic: paralysis, wasting away

Question 10

isolation of ASF

Answer 10

isolation in buffy coat culture only!!

Question 11

African swine virus vs. classical swine fever

Answer 11

very similar diseases!
ASF - asfar (vaccine doesn’t work)
CSF - flavi (vaccine work)