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INORGANIC CHEMISTRY > PICLEC: MODULE 3 > Flashcards

PICLEC: MODULE 3 Flashcards

1
Q

OFFICIAL ACIDS:
Treatment of gastric achlorhydria (lack of hcl)

A

DILUTED HYDROCHLORIC ACID

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2
Q

Arsenic chloride soution

A

ARSENIOUS ACID

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3
Q

“Nitromuriatic acid”, “aqua regia” — kingly water

A

NITROHYDROCHLORIC ACID

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4
Q

“Eau forte”, “Aqua fortis”— Strong water

A

NITRIC ACID

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5
Q

used for manufacturing explosives and nitrates. (act as preservative)

A

NITRIC ACID

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6
Q

OFFICIAL ACIDS

A

HYDROCHLORIC ACID
NITRIC ACID
PHOSPHORIC ACID
SULFURIC ACID
BORIC ACID

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7
Q

“Monsel’s solution”

A

FERROUS SUBSULFATE SOLUTION

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8
Q

the nitric acid converts the bismuth subnitrate to nitrate

A

BISMUTH MAGMA

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9
Q

Hydrochloric acid sub solutions

A

HYDROCHLORIC ACID
DILUTED HYDROCHLORIC ACID
ARSENIOUS ACID
NITROHYDROCHLORIC ACID

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10
Q

nitric acid sub solutions

A

FERROUS SUBSULFATE
MERCURIC NITRATE SOLUTION
BISMUTH MAGMA

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11
Q

Phosphoric acid sub solutions

A

PHOSPHORIC ACID USP (85-88% of H3PO4)
DILUTED PHOSPHORIC ACID (9.5-10.5 % of H3PO4)

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12
Q

Sulfuric acid sub solutions

A

SULFURIC ACID USP ( 94-95% H2SO4)
SACCHARATED FERROUS CARBONATE (diluted H2SO4)

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13
Q

Boric acid sub solutions

A

KAOLIN CATAPLASM
BORIC ACID SOLUTION
BORIC ACID OINTMENT
LISTER’S SOLUTION (antiseptic solution)
COMPOUN ZINC SULFATE POWDER (Antiseptic powder)

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14
Q

OFFICIAL BASES

A

SODIUM HYDROXIDE
POTASSIUM HYDROXIDE
CALCIUM HYDROXIDE
SODIUM CARBONATE
STRONG AMMONIA SOLUTION
DILUTED AMMONIA SOLUTION

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15
Q

Used as standard solution in acid-base titrations

A

SODIUM HYDROXIDE

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16
Q

Similar to NaOH, more deliquescent, stronger and more expensive

A

POTASSIUM HYDROXIDE

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17
Q

Mixture of compounds, resists pH changes upon addition of small quantities of acid or alkali

maintain pH of medicinals at optimal limits

A

BUFFERS

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18
Q

Used in formulation of opthalmic solutions

A

PHARMACEUTICAL BUFFERS

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19
Q

sodium phosphate + NaCl (pH 6-8)

“Phosphate buffered saline”

A

sorensen phosphate buffer

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20
Q

boric acid + sodium carbonate +KCL

A

GIFFORD’S BUFFER

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21
Q

Boric acid + sodium carbonate + NaCl

A

ATKIN’S AND PANTIN BUFFER

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22
Q

Boric acid + sodium BORATE + NaCl

A

FELDMAN’S BUFFER / PALITZSCH BUFFER

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23
Q

Raw material, inactive ingredients, medicinal vehicle, solvent

A

Water

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24
Q

Manufacture of pharmaceutical products, active pharmaceutical ingredients, APIs intermediates, compedial articles, and analytical Reagents as well as cleaning applications

A

Water

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25
Q

Varying amounts of suspended matter clay, sand, microorganisms, and fragments of plants and animals. Has distinct taste

A

Natural water, mineral water, Spring water, natural spring/water

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26
Q

Types of water hardness

A

Temporary and permanent hardness

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27
Q

Can be seen in shower heads; has soluble calcium and magnesium bicarbonates

Can be soften by boiling or lime process

A

Temporary hardness

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28
Q

Has calcium and magnesium chloride and sulfates

A

Permanent hardness

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29
Q

Produced on-site where they are used

A

bulk monographed water

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30
Q

Bulk monographed water

A

Purified water
Water for injection
Water for hemodialysis
Pure stream,

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31
Q

Excipient in the production of non parenteral prep in pharmaceutical app.

Not sterile

A

Purified water

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32
Q

Production of parenteral prep has endotoxin content must be controlled

Not sterile

A

Water for injection

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33
Q

For hemodialysis app.
Minimal Qual. Of source water = drinking water

A

WATER FOR HEMODIALYSIS

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34
Q

“Clean strem”

A

Pure stream

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35
Q

Porous load sterilization process, used to control humidity inside processing vessels

Minimal Qual of source water= drinking water

A

Pure stream

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36
Q

Sterile monigraphed water

A

Sterile purified water
Sterile water for injection
Bacteriostatic water for injection
Sterile water for irrigation
Sterile water for inhalation

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37
Q

Produced, packaged, and sterilized to preserve microbial quality throughout shelf life

A

Sterile monographed water

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38
Q

Purified water packaged an dredered sterile

A

Sterile purified water

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39
Q

Water for injection packaged and rendered sterile, SINGLE DOSE containers not more than 1L

A

sterile water for injection

40
Q

Water for injection added one or more suitable antimicrobial preservatives, used as diluent In pre of parenteral prod. Multi dose container not more than 30mL

A

Bacteristatic water for injection

41
Q

Water for injection, SINGLE DOSE container that may e LARGER then 1L and allow rapid delivery of contents

A

WTAER FOR IRRIGATION

42
Q

Water for injection, used in inhalators and prep for inhalation sol’n

A

STERILE WATER FOR INHALATION

43
Q

Nonmonographed water

A

Drinking water
Carbon dioxide free water
Distilled water
Deionized water

44
Q

“Potable water”

A

DRINKING WATER

45
Q

Prescribed source of feed water for prod. Of bulk monographed water pharmaceutical waters

A

DRINKING WATER

46
Q

Purified water vigorously boiled for not less than 5 mins, cool and protected from absorption of atmospheric carbon dioxide

A

Carbon-dioxide free water

47
Q

Vaporizing drinking water or higher quality of water and condensing into pure state

A

DISTILLED WATER

48
Q

Produced by ion exchange process in which actions and anions are replaced with hydrogen and hydroxide

A

Deionized water

49
Q

Inted to come direct contact with pharmaceutical products

A

GLASS CONTAINERS

50
Q

Types of glass containers

A

Type I ( BOROSILICATE GLASS)
TYPE II ( TREATED SODA LIME SILICA
TYPE III (SODA LIME SILICA

51
Q

Decreases coefficient in Pyrex glass

A

BORON

52
Q

This glass is suitable for parenteral and non parenteral use

A

TYPE I (BOROSILICATE GLASS)

53
Q

This glass is suitable for most acidic and neutral aqueous products for parenteral and nonparenteral

A

TYPE II ( TREATED SODA LIME SILICA)

54
Q

This glass is not used for parenteral products or for powders for parenteral use

A

TYPE III (SODA LIME SILICA)

55
Q

Used to differentiate type of glass

A

GLASS GRAINS TEST

56
Q

Antioxidants solutions

A

Hypophosphorous acid
Sulfur dioxide
Sodium metabisulfite
Nitrogen gas
Argon gas

57
Q

Reduce the oxidation of active substances and excipients in finished product

A

ANTIOXIDANTS

58
Q

Powerful reducing agent (prevents oxidation from products)
Ferrous iodide syrup

A

HYPOPHOSPHOROUS ACID

59
Q

Preservative in food, drugs and beverages

A

SULFUR DIOXIDE

60
Q

Sulfur dioxide source

A

SODIUM METABISULFITE

61
Q

Cod Liver oil and vitamin prep
Use to displace oxygen and moisture containing air in packaging material to extend shelf life

A

NITRIGEN GAS

62
Q

Used as preservative

A

ARGON GAS

63
Q

Increase refractive index

A

LEAD

64
Q

Principal action in the intracellular fluid

A

POTASSIUM

65
Q

Principal action in extracellular fluid

A

SODIUM

66
Q

Principal ANION intracellular fluid

A

PHOSPHATE

67
Q

Principal ANION extracellular fluid

A

CHLORIDE

68
Q

2nd most abundant CATION in the ICF

A

MAGNESIUM

69
Q

2nd most abundant CATION in the ECF

A

CALCIUM

70
Q

2n most abundant in extracellular fluid

A

BICARBONATE

71
Q

ELECTROLYTE REPLENISHERZ

A

SODIUM CHLORIDE
POTASSIUM CHLORIDE
CALCIUM CHLORIDE

72
Q

Replenish the body’s electrolyte concentration the dehydration

A

ELECTROLYTE REOLENISHER

73
Q

Systematic alkalizer

A

SODIUM BICARBONATE
POTASSIUM BICARBONATE
SODIUM CITRATE
POTASSIUM CITRATE

74
Q

Normal physiological pH

A

7.35 - 7.45

75
Q

Used to manage disorders associated with low pH

A

SYSTEMATIC ALKALIZER

76
Q

Neutralize alkaline body fluid, particularly blood in patients who are suffering from systematic alkalosis

A

SYSTEMATIC ACIDIFIERS

77
Q

Systematic alkalizer

A

SODIUM BIPHOSPHATE
CALCIUM CHLORIDE
AMMONIUM CHLORIDE

78
Q

Form an integral part of one or more enzymes in a metabolic or biochemical process

A

ESSENTIAL AND TRACE ELEMENTS

79
Q

Catakytic site of the enzymes and oxygen transporting proteins

A

IRON

80
Q

COfactor of many enzymes in redox reactions

A

COPPER

81
Q

Enhances the action of insulin and manages blood glucose concentration

A

ZINC

82
Q

Essential role in development and maintenance of the immune system

A

ZINC

83
Q

Antioxidant that protects cells from damage due to free radicals

A

MANGANESE

84
Q

Required to potntate insulin for normal glucose metabolism

A

CHROMIUM

85
Q

Moco is used by the enzymes to catalyze diverse redox reactions

A

MOLYDEMNUM

86
Q

Antioxidant and protects against the actions of free radicals and carcinogenic factors

A

SELENIUM

87
Q

Integral part of vitamin b12 (cyanocobalamin)

A

COBALT

88
Q

Present in all peptides, proteins, and enzymes that contain cysteine and methionine amino acids

A

SULFUR

89
Q

Integral component of thyroid hormones for cellular metabolism (thyroxin and triiodothyronine)

A

IODINE

90
Q

Gastric antacids

A

MAGNESIUM ANTACIDS
ALUMINUM ANTACIDS
CALCIUM ANTACIDS
MISCELLANEOUS OFFICIAL ANTACIDS

91
Q

Magnesium antacids

Common side effect of Magnesium is DIARRHEA

A

MAGNESIUM HYDROXIDES
MAGNESIUM CARBONATE
MAGNESIUM OXIDE
MAGNESIUM PHOSPHATE
MAGNESIUM TRISILICATE
ALUMINA AND MAGNESIA

92
Q

Aluminum antacids

Side effects CONSTIPATION

A

ALUMINUM HYDROXIDE
ALUMINUM PHOSPHATE
DIHYDROXYALUMINUM SODIUM AMINO ACETATE
DYHYDROXYALUMINUM SODIUM CARBONATE
ALUMINA, MAGNESIA, AND CALCIUM CARBONATE
ALUMINA AND MAGNESIUM TRISILICATE
ALUMINA AND MAGNESIA

93
Q

Calcium antacids

A

PRECIPITATED CALCIUM CARBONATE
CALCIUM CARBONATE ADN MAGNESIA
CLACIUM AND MAGNESIIUM CARBONATE
MAGALDRATEX ALUMINUM MAGNESIUM HYDROXIDE SULFATE

94
Q

Miscellaneous official antacids

A

BISMUTH SUBCARBONATE
MILK OF BISMUTH
SODIUM BICARBONATE
POTASSIUM BICARBONATE

95
Q

Defoaming agent, antiflatulence

A

SIMETHICONE

96
Q

Protective and adsorbents
- symptom and not a disease
Impair digestion and or absorption
Increase bulk - stimulates peristalsis
Can lead to dehydration

A

Diarrhea

INORGANIC CHEMISTRY (19 decks)

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