PICLEC: GROUP VIIIA & VIIIB Flashcards
This group is known as ‘The Noble gas’
- Inert gas/elements
- Chemically inert/stable/unreactive
- Monoatomic gases
+ all except Radon(Rn) occur in atmosphere
GROUP VIIIA - THE NEON GROUP
GROUP VIIIA - THE NEON GROUP
- Produced during natural decay of radium
RADON
GROUP VIIIA - NEON
- “Sun”
HELIUM
GROUP VIIIA - NEON
- “Sun”
- Mixed with Anesthetic gases
- Natural air = 20% Oxygen, 79% Nitrogen
- Artificial air = 20% Oxygen, 80% Helium
HELIUM
(TIP: Helium & Artificial = Hartificial)
GROUP VIIIA - NEON
- “New”
NEON
GROUP VIIIA - NEON
- “New”
- Used in signs due to bright reddish-orange light
NEON
GROUP VIIIA - NEON
- “Lazy”
ARGON
GROUP VIIIA - NEON
- “Lazy”
- Used to displace oxygen and moisture-containing air in packaging material to extend the shelf- lives of the contents
ARGON
GROUP VIIIA - NEON
- “Hidden”
KRYPTON
GROUP VIIIA - NEON
- “Hidden”
- Used in some photographic flashes for high-speed photography
KRYPTON
(TIP: dapat hidden siya since ito yung weakness ni Superman)
GROUP VIIIA - NEON
- Anticancer (Anti-neoplastic) medications
RADON
GROUP VIIIB - ELEMENTS
- This element’s name Came from the Greek word ‘Kupfernickle’ = “Satan or devil’s copper”
NICKLE
GROUP VIIIB - ELEMENTS
- It is used extensively in the form of Alloys for utensils, coins, and surgical instruments
NICKLE
GROUP VIIIB - ELEMENTS
- It is made up of Nickel (Ni) + Copper (Cu) + Zinc (Zn)
GERMAN SILVER
GROUP VIIIB - ELEMENTS
- This element is Used as Adsorbent (dumidikit) for hydrogen in gas analysis
- Alloys with gold = Jewelry, dental practice, coating reflectors
PALLADIUM
GROUP VIIIB - ELEMENTS
- This element’s Synonyms are:
1. Spanish name ‘Platina’ = “Silver”
PLATINUM
GROUP VIIIB - ELEMENTS
- This element’s Properties are:
1. Resistant to corrosion
2. Dissolves in Aqua regia
3. More expensive jewelry than Gold
PLATINUM
GROUP VIIIB - ELEMENTS
- This element is Used in the preparations of Crucibles, Dishes, and wires
PLATINUM
GROUP VIIIB - PLATINUM
- Finely divided form
- A powerful catalyst (catalyst=speeds up reaction)
PLATINUM BLACK
GROUP VIIIB - PLATINUM
ORGANOPLATINUM COMPOUNDS
(TIP: They all have ‘platin’)
- CISPLATIN
- CARBOPLATIN
- OXALIPLATIN
- SATRAPLATIN
GROUP VIIIB - PLATINUM
ORGANOPLATINUM COMPOUNDS:
- Anticancer agent
- Binds to DNA and causes cross-linking, which triggers the programmed cell death(Apoptosis)
- Discovered by Rosenberg in 1965 serendipitously (accidental)
CISPLATIN
GROUP VIIIB - PLATINUM
ORGANOPLATINUM COMPOUNDS:
- Its Side effects are:
1. Nausea and Vomitting
2. Nephrotoxicity - Kidney poisoning
In Dose-limiting:
3. Ototoxicity - Loss of high-frequency hearing
4. Peripheral neuropathy (neuro=nerves, pathy=pain/damage) - Damage to nerves of the peripheral nervous system
5. Myelosuppression - Bone marrow (home of WBC) suppression, Reduces the patient’s WBC count and makes them susceptible to Infections.
CISPLATIN
GROUP VIIIB - PLATINUM
ORGANOPLATINUM COMPOUNDS:
- 2nd Generation Pt-based Anticancer drug
- Less reactive and has less Nephrotoxic and Ototoxic
- More Myelosuppressive
(lesser dose, less reaction and less toxic)
CARBOPLATIN
GROUP VIIIB - PLATINUM
ORGANOPLATINUM COMPOUNDS:
- 3rd Generation Pt+based Anticancer drug
- Most effective combination with
1. 5-Fluorouracil and Leucoyorin in the Treatment of metastatic (cncer has metastasized) carcinomas of the Colo/Rectum
OXALIPLATIN
GROUP VIIIB - PLATINUM
ORGANOPLATINUM COMPOUNDS:
- Orally active (can take ‘PO’ - “Per orem”, “Per oral”)
- Milder toxicity
- No cross-resistance
- Not approved by FDA
STRAPLATIN
GROUP VIIIB - ELEMENTS
- This element’s Name came from the Latin name: Ferum = “Strong”
- Widely used metal
+ Low production
+ High strength
+ Fe + C = STEEL
IRON
GROUP VIIIB - IRON
- Iron-containing water
CHALYBEATE WATER
GROUP VIIIB - ELEMENTS
- This element’s Occurrence are:
1. Fe3O4 = MAGNETITE
2. Fe2O3 = HEMATITE
3. FeS2 = PYRITE (Fool’s gold)
IRON
GROUP VIIIB - IRON
- “Fool’s gold’’
PYRITE
GROUP VIIIB - ELEMENTS
- This element Exist as:
1. Elemental Iron
2. Ferrous Salts (Fe+2)
3. Ferric Salts (Fe+3)
IRON
GROUP VIIIB - ELEMENTS
- It exists as Pure Iron resistant to Oxidation
- It exists as Rusting (ferric oxide) is probably dur to impurities
ELEMENTAL IRON
GROUP VIIIB - ELEMENTS
- It exists as Divalemt, Reduced form
- It exists as Colorless in Anhydrous form
- Green din hydrated form
- Reducing agents
FERROUS SALT (Fe+2)
GROUP VIIIB - ELEMENTS
- This element Exists as Trivalent, oxidize form
- Yellowish to brown in Anhydrous form
- Oxidizing agents
- Give red ppt with tannins (food in plants)
FERRIC SALTS
GROUP VIIIB - ELEMENTS
- This element is Used as:
1. Astringent
2. Styptic - Stops bleeding when applied to a wound
3. Hamatinic - Stimulates RBC production
IRON
GROUP VIIIB - ELEMENTS
1. Black stool - common side effect of iron preparation
2. Functions in Human body:
- Iron as an Essential Trace Element (found in body with less concentration)
- HEMOGLOBIN
- MYOGLOBIN
- CYTOCHROMES
3. Iron deficiency
- Lethargy (nanlalambot) and weakness
- Iron supplementation (solution for Anemia, best used w/ Ascorbic acid)
IRON
GROUP VIIIB - IRON
FUNCTIONS IN HUMAN BODY:
- Oxygen- transport metalloprotein in RBC
HEMOGLOBIN or HAEMOGLOBIN
GROUP VIIIB - IRON
FUNCTIONS IN HUMAN BODY:
- Facilitates O2 use and Storage in muscles
(Myo=Muscles)
MYOGLOBIN
GROUP VIIIB - IRON
FUNCTIONS IN HUMAN BODY:
- Transport electron
CYTOCHROMES
GROUP VIIIB - IRON
- 8x less effective thanFerrous sulfate
- Hematinic
FERRIC AMMONIUM CITRATE
GROUP VIIIB - IRON
- Treatment of Anemia requiring Iron and Arsenic
FERRIC CACODYLATE
GROUP VIIIB - IRON
- Astringent
- Styptic
- Hematinic
FERRIC CHLORIDE
GROUP VIIIB - IRON
- Red and Yellow for,
- Colorant, Stimulate skin color (e.g. Calamine)
FERRIC OXIDE
GROUP VIIIB - IRON
- Ferrous carbonate mass
- Ferrous carbonate pills
FERROUS CARBONATE
GROUP VIIIB - IRON
FERROUS CARBONATE:
- “Vallet’s Mass”
- Hematinic
FERROUS CARBONATE MASS
GROUP VIIIB - IRON
FERROUS CARBONATE:
- “Vallet’s Mass”
FERROUS CARBONATE MASS
GROUP VIIIB - IRON
FERROUS CARBONATE:
- “Chalybeate Pills”, “Ferruginous Pills”
- Hematinic
FERROUS CARBONATE PILLS
GROUP VIIIB - IRON
FERROUS CARBONATE:
- “Chalybeate Pills”, “Ferruginous Pills”
FERROUS CARBONATE PILLS
GROUP VIIIB - IRON
- “Green vitriol” (FeSO4.5H2O)
- Most common, Least expensive
- Common side effect: Gastric discomfort
FERROUS SULFATE
GROUP VIIIB - IRON
- “Green vitriol” (FeSO4.5H2O)
FERROUS SULFATE
GROUP VIIIB - IRON
- Less gastric irritation than Ferrous sulfate (ex. Sangobion)
FERROUS GLUCONATE
GROUP VIIIB - IRON
- Most expensive
FERROUS FUMARATE
GROUP VIIIB - IRON
- “Dialyzed iron”
- Antidote: Arsenic poisoning
FERRIC HYDROXIDE
GROUP VIIIB - IRON
- “Dialyzed iron”
FERRIC HYDROXIDE
GROUP VIIIB - IRON
- “Mohr’s salt”
- Used as an indicator in Silver(Ag) titrations
FERROUS AMMONIUM SULFATE
GROUP VIIIB - IRON
- “Mohr’s salt”
FERROUS AMMONIUM SULFATE
GROUP VIIIB - IRON
- “Red prussiate of Potash’’
POTASSIUM FERRICYANIDE
(TIP: Ferri = Rid (Red)
GROUP VIIIB - IRON
- “Yellow prussiate of potash”
POTASSIUM FERROCYANIDE
(TIP: FerrO=YellOw)
GROUP VIIIB - IRON
- “Turnbull’s Blue’’
FERROUS FERRICYANIDE (Fe3[Fe(CN)6]2)
GROUP VIIIB - IRON
- “Prussian Blue”
- Antidote: Thallium poisoning
FERRIC FERROCYANIDE (Fe4[Fe(CN)6]3)
GROUP VIIIB - ELEMENT
- This element’s name Came from the German word ‘der Kobold’ =“Goblin or Gnome”
COBALT
GROUP VIIIB - ELEMENT
- This element’s Properties are:
1. Pinkish white metal
2. Stimulate Hematopoiesis (hema=blood, poiesis=formation/creation) - Formation of Blood cellular components
3. Parenteral (via veins): BP lowering, capillary damage
4. Oral: omitting, and diarrhea
COBALT
GROUP VIIIB - COBALT
- “Rinman’s Green”
- Paint pigment
CONALTOUS OXIDE
GROUP VIIIB - COBALT
- “Rinman’s Green’’
COBALTOUS OXIDE
GROUP VIIIB - COBALT
- Astringent
- Antiseptic powder
COBALTO-COBALTIC OXIDE
GROUP VIIIB - COBALT
- Basis for invisible or sympathetic inks
- Turns Blue when warmed
COBALTOUS CHLORIDE
GROUP VIIIB - ELEMENT
- Alloy of Rh+ Pt = Harder, more durable than Pt alone
RHODIUM
GROUP VIIIB - ELEMENT
- Heaviest, densest element
OSMIUM
GROUP VIIIB - OSMIUM
- “Osmic acid”
- Used for Hardening and Coloring (black) Histological specimens
OSMIUM TETROXIDE
GROUP VIIIB - OSMIUM
- “Osmic Acid”
OSMIUM TETROXIDE