PICLEC: GROUP VIIIA & VIIIB Flashcards
This group is known as ‘The Noble gas’
- Inert gas/elements
- Chemically inert/stable/unreactive
- Monoatomic gases
+ all except Radon(Rn) occur in atmosphere
GROUP VIIIA - THE NEON GROUP
GROUP VIIIA - THE NEON GROUP
- Produced during natural decay of radium
RADON
GROUP VIIIA - NEON
- “Sun”
HELIUM
GROUP VIIIA - NEON
- “Sun”
- Mixed with Anesthetic gases
- Natural air = 20% Oxygen, 79% Nitrogen
- Artificial air = 20% Oxygen, 80% Helium
HELIUM
(TIP: Helium & Artificial = Hartificial)
GROUP VIIIA - NEON
- “New”
NEON
GROUP VIIIA - NEON
- “New”
- Used in signs due to bright reddish-orange light
NEON
GROUP VIIIA - NEON
- “Lazy”
ARGON
GROUP VIIIA - NEON
- “Lazy”
- Used to displace oxygen and moisture-containing air in packaging material to extend the shelf- lives of the contents
ARGON
GROUP VIIIA - NEON
- “Hidden”
KRYPTON
GROUP VIIIA - NEON
- “Hidden”
- Used in some photographic flashes for high-speed photography
KRYPTON
(TIP: dapat hidden siya since ito yung weakness ni Superman)
GROUP VIIIA - NEON
- Anticancer (Anti-neoplastic) medications
RADON
GROUP VIIIB - ELEMENTS
- This element’s name Came from the Greek word ‘Kupfernickle’ = “Satan or devil’s copper”
NICKLE
GROUP VIIIB - ELEMENTS
- It is used extensively in the form of Alloys for utensils, coins, and surgical instruments
NICKLE
GROUP VIIIB - ELEMENTS
- It is made up of Nickel (Ni) + Copper (Cu) + Zinc (Zn)
GERMAN SILVER
GROUP VIIIB - ELEMENTS
- This element is Used as Adsorbent (dumidikit) for hydrogen in gas analysis
- Alloys with gold = Jewelry, dental practice, coating reflectors
PALLADIUM
GROUP VIIIB - ELEMENTS
- This element’s Synonyms are:
1. Spanish name ‘Platina’ = “Silver”
PLATINUM
GROUP VIIIB - ELEMENTS
- This element’s Properties are:
1. Resistant to corrosion
2. Dissolves in Aqua regia
3. More expensive jewelry than Gold
PLATINUM
GROUP VIIIB - ELEMENTS
- This element is Used in the preparations of Crucibles, Dishes, and wires
PLATINUM
GROUP VIIIB - PLATINUM
- Finely divided form
- A powerful catalyst (catalyst=speeds up reaction)
PLATINUM BLACK
GROUP VIIIB - PLATINUM
ORGANOPLATINUM COMPOUNDS
(TIP: They all have ‘platin’)
- CISPLATIN
- CARBOPLATIN
- OXALIPLATIN
- SATRAPLATIN
GROUP VIIIB - PLATINUM
ORGANOPLATINUM COMPOUNDS:
- Anticancer agent
- Binds to DNA and causes cross-linking, which triggers the programmed cell death(Apoptosis)
- Discovered by Rosenberg in 1965 serendipitously (accidental)
CISPLATIN
GROUP VIIIB - PLATINUM
ORGANOPLATINUM COMPOUNDS:
- Its Side effects are:
1. Nausea and Vomitting
2. Nephrotoxicity - Kidney poisoning
In Dose-limiting:
3. Ototoxicity - Loss of high-frequency hearing
4. Peripheral neuropathy (neuro=nerves, pathy=pain/damage) - Damage to nerves of the peripheral nervous system
5. Myelosuppression - Bone marrow (home of WBC) suppression, Reduces the patient’s WBC count and makes them susceptible to Infections.
CISPLATIN
GROUP VIIIB - PLATINUM
ORGANOPLATINUM COMPOUNDS:
- 2nd Generation Pt-based Anticancer drug
- Less reactive and has less Nephrotoxic and Ototoxic
- More Myelosuppressive
(lesser dose, less reaction and less toxic)
CARBOPLATIN
GROUP VIIIB - PLATINUM
ORGANOPLATINUM COMPOUNDS:
- 3rd Generation Pt+based Anticancer drug
- Most effective combination with
1. 5-Fluorouracil and Leucoyorin in the Treatment of metastatic (cncer has metastasized) carcinomas of the Colo/Rectum
OXALIPLATIN
GROUP VIIIB - PLATINUM
ORGANOPLATINUM COMPOUNDS:
- Orally active (can take ‘PO’ - “Per orem”, “Per oral”)
- Milder toxicity
- No cross-resistance
- Not approved by FDA
STRAPLATIN
GROUP VIIIB - ELEMENTS
- This element’s Name came from the Latin name: Ferum = “Strong”
- Widely used metal
+ Low production
+ High strength
+ Fe + C = STEEL
IRON
GROUP VIIIB - IRON
- Iron-containing water
CHALYBEATE WATER