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Endo Exam 2 > Physiology Review III > Flashcards

Physiology Review III Flashcards

1
Q

morning sickness

A

hCG

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2
Q

gestational hyperthyroidism

A

hCG binds TSH receptors

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3
Q

other hCG effects

A

leydig - testosterone

fetal adrenal cortex

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4
Q

progesterone synthesis

A

CYP11A1, 3B HSD

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5
Q

progesterone

A

decreased uterine contractions

  • increased secretions
  • increased fat deposition
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6
Q

estrogen

A

necessary for parturition

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7
Q

E:P ration

A

decreased progesterone - allows PRL to act

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8
Q

hPL/hCS

A

lipolytic

increased glucose for fetus

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9
Q

placental limitations

A

no cholesterol

no enzymes for estrogen

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10
Q

PRL

A

estrogen stimulates release

lactotroph hypertrophy

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11
Q

sheehans syndrome

A

lactotroph hypertrophy

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12
Q

ADH changes

A

lower threshold

progesterone effect

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13
Q

thyroid changes

A

total raises
free same

bc of TGB

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14
Q

11-beta DH type 2

A

inactivates cortisol

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15
Q

increased aldosterone?

A

estrogen
-increased angiotensinogen and renin

but progesterone blunts action

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16
Q

increased plasma volume

A

incrased NaCl retention - aldosterone

increased water retention - ADH

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17
Q

stroke volume

A

decreased
IVC compression
decreased VR, EDV, SV

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18
Q

CO distribution

A

uterus, renal, skin, heart, breasts

same - brain, gut, skeleton

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19
Q

TPR

A

decreased
low R circuit
vasodilation
low viscosity

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20
Q

edema

A

increased V pressure in legs

decreased capillary osmotic P (less proteins)

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21
Q

alveolar ventilation

A

increased

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22
Q

PCO2

A

decreased

respiratory alkalosis

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23
Q

respiratory alkalosis

A

renal compensation

-increased bicarb secretion

24
Q

fetal Hg

A

higher affinity

left shift

25
CO
increased HR and SV
26
renal
increased RBF and GFR Na retention, water retention decreased serum Na
27
GI
reflux progesterone - decreased emptying, LES tone increased abdomen P decreased mobility
28
mom nutrition
needs protein, iron, folate
29
quiescent uterus
relaxin and progesterone
30
braxton hicks
weak contractions | false labor
31
stages of parturition
1 contractions - dilation < 10cm 2 > 10cm to delivery 3 delivery of placenta
32
prostaglandins
stimulated by estrogen, oxytocin, stretch initiate labor** soft cervix can be used to induce labor
33
aspirin
inhibits prostaglandins
34
ferguson reflex
oxytocin - increased contractions - increased positive feedback for oxytocin
35
estrogen effects end of term
more gap junctions more oxytocin receptors more prostaglandin synthesis
36
CRH
from placenta | -increase sensitivity to prostaglandins and oxytocin in uterus
37
relaxin
from CL and placenta | soften ligaments
38
cortisol increase
surfactant in fetal lungs
39
nipple
stratified squamuos dry melanocytes elastic fivers meissners and pacinian corpuscles
40
functional unit
lobule
41
myoepithelium
around alveoli no nerves only oxytocin
42
intralobular CT
loose
43
interlobular CT
dense
44
mammogenesis
estrogen
45
estrogen breasts
ducts
46
progesterone breasts
alveoli
47
breast cancer
lots have estrogen receptor different Tx pre and post menopause
48
colostrum
IgG, nutrients, fat
49
sucking
1 - decreased dopamine, increased PRL 2 - increased oxytocin 3 - decreaed GnRH - inhibit ovarian cycle
50
cow fat
high protein - casein
51
breast milk immunity
IgA WBC, M0s growth factors
52
mammogenic
E/P
53
lactogenic
estrogen, hCS, decreased progesterone
54
galactokinetic
oxytocin
55
galactopoietic
PRL

Endo Exam 2 (17 decks)

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