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Endo Exam 2 > Physiology Review III > Flashcards

Physiology Review III Flashcards

1
Q

morning sickness

A

hCG

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2
Q

gestational hyperthyroidism

A

hCG binds TSH receptors

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3
Q

other hCG effects

A

leydig - testosterone

fetal adrenal cortex

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4
Q

progesterone synthesis

A

CYP11A1, 3B HSD

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5
Q

progesterone

A

decreased uterine contractions

  • increased secretions
  • increased fat deposition
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6
Q

estrogen

A

necessary for parturition

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7
Q

E:P ration

A

decreased progesterone - allows PRL to act

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8
Q

hPL/hCS

A

lipolytic

increased glucose for fetus

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9
Q

placental limitations

A

no cholesterol

no enzymes for estrogen

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10
Q

PRL

A

estrogen stimulates release

lactotroph hypertrophy

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11
Q

sheehans syndrome

A

lactotroph hypertrophy

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12
Q

ADH changes

A

lower threshold

progesterone effect

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13
Q

thyroid changes

A

total raises
free same

bc of TGB

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14
Q

11-beta DH type 2

A

inactivates cortisol

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15
Q

increased aldosterone?

A

estrogen
-increased angiotensinogen and renin

but progesterone blunts action

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16
Q

increased plasma volume

A

incrased NaCl retention - aldosterone

increased water retention - ADH

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17
Q

stroke volume

A

decreased
IVC compression
decreased VR, EDV, SV

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18
Q

CO distribution

A

uterus, renal, skin, heart, breasts

same - brain, gut, skeleton

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19
Q

TPR

A

decreased
low R circuit
vasodilation
low viscosity

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20
Q

edema

A

increased V pressure in legs

decreased capillary osmotic P (less proteins)

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21
Q

alveolar ventilation

A

increased

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22
Q

PCO2

A

decreased

respiratory alkalosis

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23
Q

respiratory alkalosis

A

renal compensation

-increased bicarb secretion

24
Q

fetal Hg

A

higher affinity

left shift

25
Q

CO

A

increased HR and SV

26
Q

renal

A

increased RBF and GFR
Na retention, water retention

decreased serum Na

27
Q

GI

A

reflux
progesterone - decreased emptying, LES tone

increased abdomen P
decreased mobility

28
Q

mom nutrition

A

needs protein, iron, folate

29
Q

quiescent uterus

A

relaxin and progesterone

30
Q

braxton hicks

A

weak contractions

false labor

31
Q

stages of parturition

A

1 contractions - dilation < 10cm
2 > 10cm to delivery
3 delivery of placenta

32
Q

prostaglandins

A

stimulated by estrogen, oxytocin, stretch

initiate labor**
soft cervix

can be used to induce labor

33
Q

aspirin

A

inhibits prostaglandins

34
Q

ferguson reflex

A

oxytocin - increased contractions - increased positive feedback for oxytocin

35
Q

estrogen effects end of term

A

more gap junctions
more oxytocin receptors
more prostaglandin synthesis

36
Q

CRH

A

from placenta

-increase sensitivity to prostaglandins and oxytocin in uterus

37
Q

relaxin

A

from CL and placenta

soften ligaments

38
Q

cortisol increase

A

surfactant in fetal lungs

39
Q

nipple

A

stratified squamuos dry
melanocytes
elastic fivers
meissners and pacinian corpuscles

40
Q

functional unit

A

lobule

41
Q

myoepithelium

A

around alveoli
no nerves
only oxytocin

42
Q

intralobular CT

A

loose

43
Q

interlobular CT

A

dense

44
Q

mammogenesis

A

estrogen

45
Q

estrogen breasts

A

ducts

46
Q

progesterone breasts

A

alveoli

47
Q

breast cancer

A

lots have estrogen receptor

different Tx pre and post menopause

48
Q

colostrum

A

IgG, nutrients, fat

49
Q

sucking

A

1 - decreased dopamine, increased PRL
2 - increased oxytocin
3 - decreaed GnRH - inhibit ovarian cycle

50
Q

cow fat

A

high protein - casein

51
Q

breast milk immunity

A

IgA
WBC, M0s
growth factors

52
Q

mammogenic

A

E/P

53
Q

lactogenic

A

estrogen, hCS, decreased progesterone

54
Q

galactokinetic

A

oxytocin

55
Q

galactopoietic

A

PRL

Endo Exam 2 (17 decks)

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