Physiology of Taste and Smell Flashcards

1
Q

What kind of receptor are those for taste and smell?

A

Chemoreceptors = stimulated by binding of particular chemicals

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2
Q

What does stimulation of taste and smell receptors induce?

A

Pleasurable or objectionable sensation

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3
Q

What do taste and smell provide a checkpoint for?

A

Quality control (ie has food gone off etc)

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4
Q

What do taste and smell influence in association with food intake?

A

Flow of digestive juices

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5
Q

What influences taste perception?

A

Information from smell receptors

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6
Q

What is gustation?

A

Term for sense of taste

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7
Q

Where are the sensory receptor cells of taste mainly packaged?

A

In taste buds

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8
Q

What are the sense organs of taste?

A

Taste buds

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9
Q

What do taste buds consist of?

A

Sensory receptor cells and support cells arranged like slices of orange

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10
Q

What is the life span of taste receptor cells?

A

About 10 days = replaced by basal cells within taste buds

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11
Q

What do taste receptor cells synapse with inside taste buds?

A

Afferent nerve fibres

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12
Q

Where are taste buds present?

A

Tongue, palate, epiglottis, pharynx

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13
Q

Where are the majority of taste buds found?

A

Sit in papillae in the tongue

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14
Q

What are the papillae of the tongue?

A

Finger-like structures which give rise to rough appearance of dorsum of tongue = seen in tongue as little red dots/raised bumps

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15
Q

How many types of papillae are in the human tongue?

A

4 types = filiform (most common, no taste buds), fungiform, vallate, foliate

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16
Q

What does the binding of taste-provoking chemicals (tastant) to receptors cells cause?

A

Alters cell ionic channels and produces depolarising receptor potential

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17
Q

What does the receptor potential created by the binding of taste-provoking chemicals cause?

A

Initiates action potentials in afferent nerve fibres which synapse with receptor cells

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18
Q

What conveys the signals from the tongue to the brain?

A

Cranial nerves = via brainstem and thalamus to cortical gustatory areas

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19
Q

What are some cranial nerves that carry afferent taste fibres to the brainstem?

A
7th  = chorda tympani branch of facial nerve
9th = glossopharyngeal
10th = vagus
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20
Q

Where does the chorda tympani branch of the facial nerve innervate in relation to taste?

A

Anterior 2/3 of the tongue

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21
Q

Where does the glossopharyngeal nerve innervate in relation to taste?

A

Posterior 1/3 of tongue

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22
Q

Where does the vagus nerve innervate in relation to taste?

A

Areas in mouth other than tongue

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23
Q

What are the five primary tastes?

A

Salty, sour, sweet, bitter, umami

24
Q

What causes a salty taste?

A

Stimulated by chemical salts, especially sodium chloride

25
How does a sour taste arise?
Stimulated by acids which contain free hydrogen ions
26
What causes someone to taste sweetness?
Receptors stimulated by configuration of glucose
27
What causes a bitter taste?
Stimulated by diverse group of tastants = alkaloids, toxic plant derivatives
28
How does a umami taste arise?
Triggered by amino acids, especially glutamate
29
Are abnormalities of taste permanent?
Not always = may be temporal or permanent
30
What is agensia?
Loss of taste function = may be caused by nerve damage, local inflammation or some endocrine disorders
31
What is hypogensia?
Reduced taste function = caused by chemotherapy or some medication
32
What is dysgensia?
Distortion of taste function
33
What are some causes of dysgensia?
Glossitis, gum infections, tooth decay, URTI, medication, neoplasm, chemotherapy, zinc deficiency
34
Where is the olfactory mucosa?
Patch of mucosa in ceiling (dorsal roof) of nasal cavity
35
What are the cell types contained in the olfactory mucosa?
Olfactory receptor cells, supporting cells, basal cells
36
What is the term for the sense of smell?
Olfaction
37
Which cells in the olfactory mucosa secrete mucus?
Basal cells
38
What are olfactory receptors?
Specialised endings of renewable afferent neurons
39
What is present in each olfactory receptor?
Each neuron has a thick short dendrite and an expanded end (called an olfactory rod)
40
What projects from olfactory rods?
Cilia = project to surface of olfactory mucosa
41
How many cilia project from each olfactory receptor neuron?
About 10-12 cilia per neuron
42
What are odorants?
Molecules that can be smelled = bind to cilia
43
What is the life span of olfactory receptors?
About 2 months
44
What act as precursors for new olfactory receptors?
Basal cells
45
What do the axons of olfactory receptors form?
Collectively form afferent fibres of olfactory nerve
46
Where do the afferent fibres of the olfactory nerve pierce?
The cribriform plate of the ethmoid bone = enter olfactory bulb in inferior surface of brain
47
Where do the olfactory bulbs transmit smell information to?
The brain
48
Where do neurons pass to once they leave the olfactory bulb?
Pass along the olfactory tract to reach the temporal lobe and olfactory areas
49
Why do odorants only reach smell receptors by diffusion during quiet breathing?
Olfactory mucosa is above the normal path or airflow
50
Why does sniffing enhance smelling?
Draws air currents upwards within the nasal cavity
51
What is needed for a substance to be smelled?
Sufficient volatility = can enter with inspired air | Sufficient water solubility = can dissolve in mucus coating olfactory mucosa
52
Are olfactory receptors equally sensitive to all substances?
No = different sensitivity for different substances
53
What is anosmia?
Inability to smell = may be temporal or permanent, due to viral infection, allergy, nasal polyps or head injury
54
What is hyposmia?
Reduced ability to smell = similar causes to anosmia, may be early sign of Parkinson's disease
55
What is dysosmia?
Altered sense of smell = differently interpreting some smells or hallucinations of smell