Physiology Flashcards
Body Fluid Compartments
Intracellular fluid
Extra cellular fluid
Types of ECF
Interstitial fluid
Blood plasma
ICF makes up how much of total body water volume?
2/3
ECF makes up how much total body water volume?
1/3
Plasma is what percentage of ECF?
25%
Interstitial fluid is what percentage of ECF?
75%
Total Body Water is how much of the total body weight?
60%
Sodium is high in which compartment?
ECF
Potassium is high in which compartment?
ICF
What ions are high in blood plasma?
Sodium, chloride, and proteins
What ions are high in ICF?
Potassium and proteins
Osmotic Pressures
Material moving into and out of the ICF must cross the cell membrane
What will a cell do in an isotonic solution?
Stay the same
What will a cell do in a hypotonic solution?
Swell/burst
What will a cell do in a hypertonic solution?
Shrink
Rate of simple diffusion relays on what factors?
Lipid solubility Molecular size Concentration gradient Membrane surface area Composition of lipid layer
Membrane permeability is proportional the what factor?
Lipid solubility
Membrane permeability is inversely related to what factor?
Molecular size
Fick’s Law of Diffusion
Rate of diffusion is proportional to the SA x concentration gradient x membrane permeability
Does facilitated diffusion use energy?
No
Facilitated diffusion uses what?
Channels and Facilitated transporters
Primary active transport does what for Secondary active transport?
Creates concentration gradient
Does secondary active transport directly use energy?
No, indirectly from concentration gradient made by primary active transport
Types of secondary active transporters?
Symporter and antiporter
What ion has to enter a muscle cell to cause a contraction?
Ca++
What is the ER called in a myocyte?
Sarcoplasmic reticulum
The sarcoplasmic reticulum stores what ion?
Ca++
What primary active transport pump has to be present to cause muscle relaxation?
Na+/K+ ATPase
What transporter is inhibited by digoxin?
Na+/K+ ATPase
Does simple diffusion have a transport maximum?
No
