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Clinical Foundations > Pathology > Flashcards

Pathology Flashcards

1
Q

Etiology

A

Cause of disease

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2
Q

Pathogenesis

A

Mechanisms of disease development

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3
Q

Morphologic changes

A

Structural alterations induced in cells and organs

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4
Q

Clinical manifestations

A

Functional consequences of morphologic changes

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5
Q

Classes of etiology

A

Genetic and acquired

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6
Q

Pathogenesis

A

Sequence of events after exposure to an injurious agent (disease)

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7
Q

Symptom

A

Problems experienced by the patient

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8
Q

Sign

A

Abnormality discovered during an examination by a clinician

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9
Q

What type of cell components have an affinity for basic dyes?

A

Anionic components (nucleic acids)

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10
Q

What cell components have an affinity for acidic dyes?

A

Cationic components

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11
Q

Hematoxylin is a _____ dye and stains _____ components a _____ color.

A

Basic, anionic, blue/purple

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12
Q

Eosin is a _____ dye and stains _____ components a _____ color.

A

Acidic, cationic, pink

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13
Q

What histology staining is used most commonly?

A

Hematoxylin and eosin combination (H&E)

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14
Q

Periodic-acid-Schiff (PAS) rxn

A

Carb-rich tissue structures and stains them purple/magenta

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15
Q

Trichromatic stains show distinctions among what kind of components?

A

Extracellular tissue components (collagen)

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16
Q

Trichromatic stains result in what colorings?

A

Nuclei-purple
Cytoplasm, keratin, and erythrocytes-bright red/orange
Collagen-bright/light blue

17
Q

Metal impregnating demonstrates what structures?

A

Filamentous structures in neurons and fibers of reticulin (type III collagen)

18
Q

What stains can be used to distinguish between elastic structures and collagen?

A

Weigert’s resorcin fuchsin, aldehyde fuchsin, and orcein

19
Q

Wright-Giemsa Stain is used on what tissues?

A

Blood or bone marrow to demonstrate types of blood cells

20
Q

What does Perls’ Prussian blue rxn stain for?

A

Iron

21
Q

Immunohistochemistry is used to identify what type of macromolecules?

A

Proteins

22
Q

Cytology

A

Studies and diagnoses disease on the cellular level

23
Q

How are cells collected for cytology?

A

Spontaneous exfoliation, mechanical exfoliation, or fine needle aspiration

Clinical Foundations (17 decks)

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