Physiology 4 Flashcards
what part of the nephron does the majority of reabsorption occur?
proximal convoluted tubule
GFR = ___ml/min
GFR = 125ml/min
what do kidneys NOT reabsorb?
creatinine
reabsorption is ________ compared to ____________ with is non-specific
reabsorption is SPECIFIC compared to FILTRATION with is non-specific
about __ml/min of filtered fluid is reabsorbed in the proximal tubule
about 80ml/min of filtered fluid is reabsorbed in the proximal tubule
(GFR = 125 ml/min → 45 ml/min flow into Loop of Henle)
is there change in osmolarity of fluid as passes through the tubule?
no
sugars, amino acids, phosphate, sulphate and lactate are all reabsorbed/secreted in the PT
H+, hippurates, neurotransmitters, bile, uric acid, drugs and toxin are all reabsorbed/secreted in the PT
sugars, amino acids, phosphate, sulphate and lactate are all reabsorbed in the PT
H+, hippurates, neurotransmitters, bile, uric acid, drugs and toxin are all secreted in the PT
name the 2 types of reabsorption that occurs along the tube into/out of the capillary
transcellular and paracellular
through the cell and in-between the cells
name the 3 types of carrier-mediated membrane transport
primary active transport
secondary active transport
facilitated diffusion
what transport:
the carrier molecule is transported coupled to the concentration gradient of an ion (usually Na+)
secondary
what transport:
passive carrier-mediated transport of a substance down its concentration gradient
facilitated diffusion
what transport:
Energy is directly required to operate the carrier and move the substrate against its concentration gradient (sodium potassium pump)
primary
the presence of what at the basolateral membrane is important in maintains the sodium gradient?
Na+-K+ ATPase pump
sodium potassium pump
what should you think of when you hear oncotic?
plasma proteins
how much glucose is normally reabsorbed into the proximal tubule?
100%
