Physiology Flashcards

1
Q

Key reproduction hormones?

A
  • GnRH
  • FSH
  • LH
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2
Q

Where is GnRH secreted from

A
  • hypothalamus
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3
Q

Role of FSH

A
  • Initates follicular growth
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4
Q

Role of LH

A
  • Stimulates further devlopment of follicles

- ovulation

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5
Q

Ovarian follicles secrete what?

A
  • oestrogen
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6
Q

What is secreted by the corpus luteum?

A
  • progesterone
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7
Q

Ovarian changes during the menstrual phase

A
  • under influence of FSH

- primary follicles -> secondary follicles

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8
Q

What happens to the uterus during the menstrual phase?

A
  • decreased oestrogen and progesterone -> prostaglandin secretion
  • prostaglandins cause arteriole constriction
  • stratum functionalis sloughs off
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9
Q

What changes occur to the ovaries during the pre-ovulatory phase

A
  • secondary follicles secrete oestrogen

- graafian follicle developes

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10
Q

What changes occur to the uterus during the pre-ovulatory phase?

A
  • oestrogens -> growth of endometrium

- stratum basilar -> mitosis -> stratum functonalis

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11
Q

What changes occur in the ovaries during the ovulatory phase?

A
  • oestrogens -> GnRH release -> LH and FSH increase
  • graafian follicle rupture
  • secondary oocyte released
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12
Q

What changes occur to the uterus during the ovulatory phase?

A
  • progesterone and oestrogen thicken the endometrium
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13
Q

Changes that occur to the ovaries during the post-ovulation phase?

A
  • corpus luteum under LH influence
  • corpus luteum -> progesterone, oestrogen, relaxin and inhibin
  • corpus luteum -> corpus albicans if no fertilisation
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14
Q

Changes that occur to the uterus post-ovulation

A
  • progesterone and oestrogen cause vascularisation and growth
  • glands secrete glycogen
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15
Q

Physical signs of pre-menstrual disorders?

A
  • breast tenderness
  • bloating
  • weight gain
  • headache
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16
Q

Treatment of pre-menstrual disorders?

A
  • COC

- GnRH agonist

17
Q

Medical management of menorrhagia?

A
  • mirena coil
  • tranexamic acid
  • coc
18
Q

surgical management of menorrhagia?

A
  • polypectomy
  • endometrial ablation
  • hysterectomy
19
Q

Causes of menorrhagia?

A
  • fibroids
  • polyps
  • adenomyosis
  • coagulopathy