Breast pathology Flashcards
1
Q
FNA classification
A
- C1 = unsatifactory
- C2 = benign
- C3 = atypical, probably benign
- C4 = Suspicious of malignancy
- C5 = malignant
2
Q
Resection of cancer options include?
A
- wide local excision
- mastectomy
3
Q
Explain normal histology of the breast
A
- myo-epithelial cells on basement membrane
- epithelial cells more luminal
4
Q
Define gynaecomastia?
A
- breast development in males without lobular development
5
Q
Causes of gynacomastia?
A
- exogenous/endogenous hormones
- cannabis
- prescription drugs
- liver disease
6
Q
Fibrocystic disease of breast presentation
A
- smooth discrete lumps
- sudden pain
- cyclical pain
- lumpiness
7
Q
Types of fibrocystic disease
A
- apocrine metaplasia
- sclerosing adenosis
- atypical hyperplasia
8
Q
Define metaplasia?
A
- change from one differentiated cell into another
9
Q
What is a hamartoma?
A
- circumscribed lesions composed of cell types normal to the breast but abnormal proportion or distribution
10
Q
Fibroadenoma is ___ dependant
A
- oestrogen
11
Q
Typical presentation of fibroadenoma?
A
- painless
- discrete
- mobile mass
- solid on USS
12
Q
Typical age presentation of fibroadenoma?
A
- 20-30s
- afro-carribean
13
Q
Why is a fibroadenoma called a biphasic tumpour
A
- epithelial and stroma tissue
14
Q
Radial scars presentation
A
- usually < 10mm
- fibroelastic core with radiating fibrosis
15
Q
Causes of fat necrosis
A
- breast trauma
- warfarin