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Pharm: Asthma/COPD > Phosphodiesterase Inhibitors > Flashcards

Phosphodiesterase Inhibitors Flashcards

1
Q

What is the single available phosphodiesterase inhibitor?

A

Roflumilast (Daliresp)

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2
Q

What is the MOA of Roflumilast?

A

Inhibits phosphodiesterase-4 which increases cAMP

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3
Q

How is Roflumilast administered?

A

Orally

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4
Q

What is the dosing frequency of Roflumilast?

A

Once daily

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5
Q

What are the ADEs of Roflumilast?

A

Severe diarrhea
HA, nausea, weight loss

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6
Q

What are the indications for use of Roflumilast?

A

COPD

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Pharm: Asthma/COPD (11 decks)

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