Mast Cell Inhibitor Flashcards
1
Q
What are the two available mast cell inhibitor agents?
A
Cromolyn
Nedocromil
2
Q
What is the MOA of mast cell inhibitors?
A
Inhibit mast cell degranulation
Inhibit release of histamine
3
Q
How are mast cell inhibitors administered?
A
Inhaled
Nebulizer
4
Q
What is the dosing frequency of mast cell inhibitors?
A
3-4x day
5
Q
Mast cell inhibitors inhibit?
A
CYP1A2
6
Q
What are the ADEs of mast cell inhibitors?
A
Cough
Irritation
Unpleasant taste
7
Q
What is the indication for use of mast cell inhibitors?
A
Prevention of asthma symptoms
8
Q
Mast cell inhibitors should not be used to?
A
Treat an asthma attack
9
Q
If your patient has systemic mastocytosis which formulation should you use?
A
Oral
10
Q
The intranasal form of mast cell inhibitors is used in what other medical condition?
A
Allergic rhinitis
