Pharmacotherapy of Sleep Flashcards
what is 1st line treatment of insomnia
non-pharm/sleep hygiene
what drug class is commonly used for insomnia
z-hypnotics and benzos
what dose of zolpidem in women and elderly
5mg
what z hypnotic has a metallic taste side effect
eszopiclone
what are side effects of zaleplon
odd sleep behaviors
potential for misuse
what are the 2 melatonin receptor agonists
ramelteon
tasimelteon
ramelteon side effects
GI upset
next day somnolence
prolactinemia
CI with fluvoxamine
what is tasimelteon typically reserved for
non 24 hr sleep wake disorder in blind adults
what are orexin receptor antagonists CI in
narcolepsy
what are the orexin drugs
suvorexant
lemborexant
daridorexant
what antidepressants can be used in sleep aid
doxepin
mirtazepine
quetiapine
trazodone
what are the side effects of doxepin
anticholinergic SEs
what is the dose of mirtazepine for sleep
7-15mg at bedtime
what is the major side effect of mirtazepine
weight gain
how to treat sleep apnea
weight loss, smoking cessation, avoid alcohol, side sleep, and CPAP
what meds can help with EDS in sleep apnea
modafinil or armodafinil
what drugs treat cataplexy
sodium oxybate
xywave
Lumryz
sodium content of sodium oxybate
high sodium
sodium content of xywave
lower sodium
age requirements of xywave
adults and kids 7+
sodium content of lumryz
high sodium
age requirements of lumryz
adults only and once nightly
what does pitolisant treat
EDS
what is CI with pitolisant
hepatic impairment
what does solriamfetol treat
EDS
what is a major SE of solriamfetol
HR and BP increase and uncontrolled psychosis
what are the drugs of choice with shift work
modafinil and armodafinil
what is first line for restless leg syndrome
gabapentin encarbil
what is second line for restless leg syndrome
pramipexole or ropinirole
