Pharmacotherapy of Sleep Flashcards by Madelynn Packer | Brainscape

Q

what is 1st line treatment of insomnia

A

non-pharm/sleep hygiene

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Q

what drug class is commonly used for insomnia

A

z-hypnotics and benzos

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Q

what dose of zolpidem in women and elderly

A

5mg

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Q

what z hypnotic has a metallic taste side effect

A

eszopiclone

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Q

what are side effects of zaleplon

A

odd sleep behaviors
potential for misuse

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Q

what are the 2 melatonin receptor agonists

A

ramelteon
tasimelteon

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Q

ramelteon side effects

A

GI upset
next day somnolence
prolactinemia
CI with fluvoxamine

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Q

what is tasimelteon typically reserved for

A

non 24 hr sleep wake disorder in blind adults

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Q

what are orexin receptor antagonists CI in

A

narcolepsy

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Q

what are the orexin drugs

A

suvorexant
lemborexant
daridorexant

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Q

what antidepressants can be used in sleep aid

A

doxepin
mirtazepine
quetiapine
trazodone

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Q

what are the side effects of doxepin

A

anticholinergic SEs

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Q

what is the dose of mirtazepine for sleep

A

7-15mg at bedtime

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Q

what is the major side effect of mirtazepine

A

weight gain

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Q

how to treat sleep apnea

A

weight loss, smoking cessation, avoid alcohol, side sleep, and CPAP

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Q

what meds can help with EDS in sleep apnea

A

modafinil or armodafinil

Q

what drugs treat cataplexy

A

sodium oxybate
xywave
Lumryz

Q

sodium content of sodium oxybate

A

high sodium

Q

sodium content of xywave

A

lower sodium

Q

age requirements of xywave

A

adults and kids 7+

Q

sodium content of lumryz

A

high sodium

Q

age requirements of lumryz

A

adults only and once nightly

Q

what does pitolisant treat

A

EDS

Q

what is CI with pitolisant

A

hepatic impairment

Q

what does solriamfetol treat

A

EDS

Q

what is a major SE of solriamfetol

A

HR and BP increase and uncontrolled psychosis

Q

what are the drugs of choice with shift work

A

modafinil and armodafinil

Q

what is first line for restless leg syndrome

A

gabapentin encarbil

Q

what is second line for restless leg syndrome

A

pramipexole or ropinirole