opthamology Flashcards
what is the main difference between open-angle and close-angle glaucoma
open-angle is where the drainage canal is obstructed and close-angle is where pressure pushes against cornea
what class of drugs is first line for open-angle glaucoma
prostaglandin analogs, beta blockers
what is the MOA of prostaglandin analogs
increase aqueous humor outflow
prostaglandin analog dosing
1 drop QHS (reduces IOP by 30%)
prostaglandin analog warnings
-darkening of iris, skin, and eyelashes
-increase in eyelash length and number
prostaglandin side effects
-blurred vision
-stinging
-increased pigmentation
-eyelash thickening
-light sensitivity
-foreign body sensation
Bimatoprost class and brand
-prostaglandin analog
-Lumigan
-Latisse (eyelash hypotrichosis)
Travoprost class and brand
-prostaglandin analogs
-travatan Z, travatan
Latanoprost class and brand
-prostaglandin
-xalatan, xelpros
Tafluprost class and brand
-prostaglandin
-zioptan
Beta-blockers MOA
reduce aqueous humor production
beta-blocker dosing
1 drop daily or BID (reduces IOP 20-30%)
beta-blocker contraindications
-sinus bradycardia
-2nd or 3rd degree heart block
-cardiogenic shock
-uncompensated cardiac failure
-bronchospastic disease
beta blocker side effects
-stinging
-blurred vision
-bradycardia
-breathing problems
-hypotension
-dizziness
-fatigue
-impotence
timolol class and brand
beta blocker
timoptic, timoptic-XE, istalol
carteolol class and brand
beta blocker
no brand
levobunolol class and brand
beta blockers
betagan
betaxolol class and brand
beta blocker
betoptic S
alpha-2 agonists moa
increase aqueous humor outflow AND reduce aqueous humor production
alpha-2 agonists dosing
1 drop TID (reduce IOP 25%)