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therapeutics 2 > Non-insulin therapy dosing > Flashcards

Non-insulin therapy dosing Flashcards

1
Q

metformin initial dose

A

500mg BID or 850mg QD (w/ meals)

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2
Q

metformin titration

A

weekly or bi-monthly. increase by 250-500mg daily

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3
Q

metformin max dose

A

2gm/day

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4
Q

metformin dosing eGFR greater than/equal to 60

A

-no contraindication
-monitor Scr annually

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5
Q

metformin dosing eGFR 45-60

A

-safe to start
-continue if already taking
-monitor Scr 3-6 months

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6
Q

metformin dosing eGFR 30-45

A

-do not start
-reduce by 50% if already taking
-monitor every 3 month

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7
Q

metformin dosing eGFR < 30

A

-do not start
-stop immediately
-may restart/hold until numbers improve

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8
Q

canagliflozin dosing eGFR > 60

A

100mg QD
max: 300mg QD

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9
Q

canagliflozin dosing eGFR 30-60

A

max: 100mg QD if no albuminuria present

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10
Q

canagliflozin dosing eGFR < 30

A

-do not start
-if already on, then 100mg QD if albumin > 300

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11
Q

dapagliflozin dosing eGFR > 45

A

-5mg QD
-max: 10mg QD

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12
Q

dapagliflozin dosing eGFR < 30

A

-do not start
-if already on, the monitor

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13
Q

empagliflozin dosing eGFR > 30

A

-10mg daily
-max: 25mg QD

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14
Q

empagliflozin dosing eGFR < 30

A

-do not start
-if on monitor

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15
Q

dosing of SGLT2 inhibitors for ESRD or HD

A

do not use

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16
Q

trulicity dosing

A

-sq weekly
-0.75mg-4.5mg
-single dose pens

17
Q

ozempic dosing

A

-sq weekly
-0.25mg x 4wks
-0.5mg then up to 2mg

18
Q

victoza dosing

A

-sq daily
-0.6mg x 7 days
-1.2mg up to 1.8mg

19
Q

Byetta dosing

A

-BID
-5mcg x 1 month
-10mcg

20
Q

bydureon bcise dosing

A

-once weekly
-2mg

21
Q

adylyxin dosing

A

-daily
-10mcg x 14 days
-20mcg

22
Q

rybelsus dosing

A

-3mg PO daily x30 days
-inc to 7mg daily
-inc to 14mg daily

23
Q

tirzepatide dosing

A

-2.5 mg SQ weekly
-adjust once a month by 2.5mg/week up to 15mg SQ weekly

24
Q

glipizide dosing

A

-start 2.5-5mg
-max is 20

25
Q

glyburide dosing

A

-start 1.25mg-5mg
-max is 10

26
Q

pioglitazone dosing

A

-start 15-30mg daily
-max 30-45mg daily

27
Q

sitagliptin CrCl > 50 dosing

A

100mg daily

28
Q

sitagliptin CrCl 30-50 dosing

A

50mg daily

29
Q

sitagliptin Crcl < 30 dosing

A

25mg daily

30
Q

saxagliptin normal Crcl dosing

A

2.5-5mg daily

31
Q

saxagliptin crcl < 50 dosing

A

2.5mg daily

31
Q

Linagliptin dosing

A

-no adjustments needed
-5mg once daily

31
Q

Alogliptin normal crcl dosing

A

-25mg daily

31
Q

alogliptin crcl 30-60 dosing

A

12.5mg daily

32
Q

alogliptin crcl < 30 dosing

A

6.25mg daily

therapeutics 2 (24 decks)

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