Pharmacology Revision

Question 1

Pharmacokinetics

Answer 1

science of the rate of movement of drugs within biological systems, as affected by the absorption, distribution, metabolism, and elimination of medications
“What your body does to the drug

Question 2

Pharmacodynamics

Answer 2

Study of the biochemical and physiologic processes underlying drug action
Mechanism of drug action
Drug-receptor interaction
Efficacy
Safety profile
“What the drug does to your body”

Question 3

Bioavailability

Answer 3

Fraction of the administered dose of drug that reaches the systemic circulation

Question 4

what is expressed as F

Answer 4

Bioavailability

Question 5

things that can alter bioavailability

Answer 5

Drug factors (Molecular weight / ionization)
Absorption (Gastric pH / health of GI tract)
First pass metabolism (hepatic) (Phenytoin may reduce F & Grapefruit juice may increase F)