Pharmacology Principles Flashcards
3 Types of Drug Names
Chemical, Generic, Trade
7 Pharmacological Principles
Pharmaceutics, Pharmacokinetics, Pharmacodynamics, Pharmacogenomics, Pharmacotherapeutics, Pharmacoeconomics, Toxicology
What is pharmaceutics
Study of how various drug forms in influence the way a drug affects the body to find the optimal design
What is Pharmacokinetics
Study of what the body does to the drug (ADME)
Absorption
Bioavailability: Percentage of drug that’s left after it has been digested
First-pass effect: Reduces bioavailability
Enteral, Parenteral, Topical
Distribution
Transport of a drug via the bloodstream to the drug’s site of action
Albumin
Most common blood protein. Inactive when a drug binds to it
Metabolism
The liver is the most responsible for metabolizing. (skeletal muscle, kidneys, lungs, plasma, intestinal mucosa)
Excretion
Elimination of drugs from the body. The primary organ responsible is the kidney. The liver and Bowel also play a role.
Steady State
Amount of drug removed via elimination = amount absorbed with each dose
Pharmacodynamics
Study of what the drug does to the body
Pharmacotherapeutics
Clinical Use of drugs to prevent and treat diseases
7 types of drug therapy
Acute, Maintenance, Supplemental, Palliative, Supportive, Prophylactic, Empirical
Pharmacoeconomics
Study of economic factors influencing the cost of drug therapy
Pharmacogenomics
Surveys the entire genome for determinants of drug response