Analgesics Part 2

Question 1

What is opioid tolerance?

Answer 1

A common physiological result of chronic opioid treatment

Question 2

What is physical dependence

Answer 2

Physiological adaption of the body to the presence of an opioid

Question 3

What is the difference between (Opioid Tolerance and Physical dependence) and Psychological dependence (Addiction)

Answer 3

An addiction is a continued craving for an opioid and the need to use the opioid for effects other than pain relief

Question 4

How does Naloxone help with management of Opioid Overdose

Answer 4

Because it has a stronger affinity to the opioid receptors than opioids

Question 5

T/F: Do not give a patient experiencing respiratory depression an opioid antagonist if they’re also exhibiting withdrawal symptoms

Answer 5

Regardless of withdrawal symptoms, when a patient experiences severe respiratory depression, an opioid antagonist should be given.

Question 6

How soon does opioid withdrawal happen in opioid-naive patients?

Answer 6

Occurs in 2 week. As a result they should be weaned off opioids after chronic usage.

Question 7

Opioid Interactions

Answer 7

Alcohol
Antihistamines
Barbiturates
Benzodiazepines
Promethazine
MAOIs

Question 8

What is Codeine Sulphate also used as?

Answer 8

An antitussive drug

Question 9

What is fentanyl?

Answer 9

Synthetic opioid used to treat moderate to severe pain

Question 10

What is the equivalent of 1mg of IV or IM hydromorphone (Dilaudid)?

Answer 10

7 mg of morphine

Question 11

When is Methadone the preferred choice?

Answer 11

Opioid of choice for detoxification treatment of opioid addicts in methadone maintenance programs

Question 12

What is the drug prototype for all opioids?

Answer 12

Morphine sulphate

Question 13

What is the composition of Percocet

Answer 13

325 mg acetaminophen and 5 mg of oxycodone

Question 14

Naloxone indication

Answer 14

Cases of suspected acute opioid overdose

Question 15

What happens if naloxone doesn’t reverse the effects of presumed opioid overdose?

Answer 15

Indicates that the condition may not be related to opioid overdose.

Question 16

What is the max dosage of acetaminophen that Health Canada is considering changing it to?

Answer 16

2g/day for older adults and those with liver disease

Question 17

Contraindications of Acetaminophen

Answer 17

Drug allergy
Liver dysfunction
Possible liver failure
G6PD deficiency

Question 18

Acetaminophen can cause dangerous interactions may occur when taken with _______ and _______________

Answer 18

Alcohol and other drugs that are hepatotoxic

Question 19

What is the recommended antidote for OD on acetaminophen

Answer 19

Acetylcysteine regimen

Question 20

What is the indication for Tramadol Hydrochloride?

Answer 20

Moderate to moderately severe pain

Question 21

What is the composition of Tramacet

Answer 21

325 mg acetaminophen and 37.5 mg tramadol

Question 22

When is feverfew used?

Answer 22

migraine headaches
menstrual cramps
inflammation
fever

Question 23

Oral forms of Opioid analgesic should be taken with ______ to minimize gastric upset

Answer 23

Food

Question 24

What do you do regarding opioids if there is a decline in the patient’s condition or if vital signs are abnormal, especially if the respiratory rate is less than 10 breaths/min

Answer 24

Withhold the dose and contact the physician

Question 25

What adverse effects must the nurse monitor for?

Answer 25

Respiratory depression may be manifested by a respiratory rate of less than 10 breaths/min, dyspnea, diminished breath sounds, or shallow breathing.

Question 26

What are the routes for fentanyl?

Answer 26

It is given through parenteral injection, transdermal patch, and sublingual tablet