Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Integrated Biomedical Sciences > Pharmacology (GI tract) > Flashcards

Pharmacology (GI tract) Flashcards

1
Q

______ secrete somatostatin and are closely associated with parietal cells.

A. Chief cells

B. D cells

C. Enterochromaffin-like

D. G cells

E. Mucus cells

A

B. D cells

Chief cells = secrete pepsinogen

D cells = secrete somatostatin

Enterochromaffin-like = secrete histamin

G cells = secrete gastrin

Parietal cells = secrete gastric acid

Mucus cells = secrete mucus and HCO3-

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

________ secrete gastrin and are deep within gastric glands.

A. Chief cells

B. D cells

C. Enterochromaffin-like

D. G cells

E. Mucus cells

A

D. G cells

Chief cells = secrete pepsinogen

D cells = secrete somatostatin

Enterochromaffin-like = secrete histamin

G cells = secrete gastrin

Parietal cells = secrete gastric acid

Mucus cells = secrete mucus and HCO3-

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

_______ secrete pepsinogen and are activated by an acidic environment.

A. Chief cells

B. D cells

C. Enterochromaffin-like

D. G cells

E. Mucus cells

A

A. Chief cells

Chief cells = secrete pepsinogen

D cells = secrete somatostatin

Enterochromaffin-like = secrete histamin

G cells = secrete gastrin

Parietal cells = secrete gastric acid

Mucus cells = secrete mucus and HCO3-

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which of the following secrete histamine?

A. Chief cells

B. D cells

C. Enterochromaffin-like

D. G cells

E. Mucus cells

A

C. Enterochromaffin-like

Chief cells = secrete pepsinogen

D cells = secrete somatostatin

Enterochromaffin-like = secrete histamin

G cells = secrete gastrin

Parietal cells = secrete gastric acid

Mucus cells = secrete mucus and HCO3-

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which of the following provides a physical and chemical border that prevents autodigestion?

A. Chief cells

B. D cells

C. Enterochromaffin-like

D. G cells

E. Mucus cells

A

E. Mucus cells

Chief cells = secrete pepsinogen

D cells = secrete somatostatin

Enterochromaffin-like = secrete histamin

G cells = secrete gastrin

Parietal cells = secrete gastric acid

Mucus cells = secrete mucus and HCO3-

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which of the following makes the lumen of stomach 2.5 million times more acidic by secreted gastric acid?

A. Chief cells

B. D cells

C. Enterochromaffin-like

D. Parietal cells

E. Mucus cells

A

D. Parietal cells

Chief cells = secrete pepsinogen

D cells = secrete somatostatin

Enterochromaffin-like = secrete histamin

G cells = secrete gastrin

Parietal cells = secrete gastric acid

Mucus cells = secrete mucus and HCO3-

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which of the following releases somatostatin and creates negative feedback to inhibit gastric acid, gastrin and pepsinogen secretion?

A. Chief cells

B. D cells

C. Enterochromaffin-like

D. G cells

E. Mucus cells

A

B. D cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which of the following secretes gastrin?

A. Parietal cells

B. G cells

A

B. G cells

Parietal cells = gastric acid

G cells = gastrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which of the following secretes gastric acid?

A. Parietal cells

B. G cells

A

A. Parietal cells

Parietal cells = gastric acid

G cells = gastrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Gastrin secretion will lead to acid secretion by which cells?

A. ECL cells

B. G cells

C. Parietal cells

D. Chief cells

E. D cells

A

C. Parietal cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Autonomic stimulation of which cells will lead to the secretion of gastrin?

A. ECL cells

B. G cells

C. Parietal cells

D. Chief cells

E. D cells

A

B. G cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Acid secretion stimulates which cells to secrete pepsinogen?

A. ECL cells

B. G cells

C. Parietal cells

D. Chief cells

E. D cells

A

D. Chief cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Somatostatin secretion will inhibit secretions from all of the following EXCEPT?

A. G cells

B. Parietal cells

C. Mucus cells

D. Chief cells

A

C. Mucus cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the 2 drugs that treat GERD?

A

Omeprazole and Cimetidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which of the following is a proton-pump inhibitor (PPI) used to treat GERD?

A. Cimetidine

B. Omeprazole

C. Celecoxib

D. Loperamide

E. Docusate

A

B. Omeprazole

Cimetidine = H2 receptor antagonist

Omeprazole = proton-pump inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which of the following is an H2 receptor antagonist used to treat GERD?

A. Cimetidine

B. Omeprazole

C. Celecoxib

D. Loperamide

E. Docusate

A

A. Cimetidine

Cimetidine = H2 receptor antagonist

Omeprazole = proton-pump inhibitor

17
Q

Long-term ______ use is a common cause of ulcers.

A. NSAIDs

B. Omeprazole

C. Celecoxib

D. Loperamide

E. Docusate

A

A. NSAIDs

18
Q

Which of the following is a COX-2 selective inhibitor?

A. NSAIDs

B. Omeprazole

C. Celecoxib

D. Loperamide

E. Docusate

A

C. Celecoxib

19
Q

All of the following are used to treat stomach ulcers EXCEPT:

A. Omeprazole

B. Cimetidine

C. Celecoxib

D. All of the above are used to treat stomach ulcers

A

C. Celecoxib

20
Q

Which of the following is used to alleviate diarrhea but is an opiod receptor agonist?

A. Docusate

B. Omeprazole

C. Celebrex

D. Loperamide

A

D. Loperamide

Loperamide does NOT cross blood brain barrier (BBB)

note: the FDA posted a warning letter about Loperamide causing serious heart problems in people who intentionally abuse loperamide for it opiod effects

21
Q

Which of the following is a stool softener used to treat constipation?

A. Docusate

B. Omeprazole

C. Celebrex

D. Loperamide

A

A. Docusate

Docusate = treats constipation

Loperamide = treats diarrhea

22
Q

Which of the following is a purgative used to induce defecation (shitting)?

A. Lactulose, MG(OH)2

B. Methylcellulose

C. Docusate

D. Bisacodyl

A

D. Bisacodyl

23
Q

All of the following are laxatives EXCEPT:

A. Lactulose

B. Docusate

C. Mg(OH)2

D. Methylcellulose

A

B. Docusate

24
Q

All of the following are used to inhibit emesis (vomiting) EXCEPT:

A. Scopolamine

B. Ondansteron

C. Ipecac

D. Dronabinol

A

C. Ipecac

Ipecac = stimulates emesis (vomiting)

Scopolamine (antimuscarininc “motion sickness”), Ondansteron (zofran) and Dronabinol (cannabinoid) are used to inhibit emesis (vomiting)

25
Q

Which of the following is an antimuscarinic used to treat motion sickness?

A. Scopolamine

B. Ondansteron

C. Ipecac

D. Dronabinol

A

A. Scopolamine

Scopolamine = antimuscarinic

Ondansteron = 5-HT3 receptor antagonist

Ipecac = stimulates vomiting

Dronabinol = cannaboid

26
Q

Which of the following is a cannabinoid used to stop you from feeling like vomiting?

A. Scopolamine

B. Ondansteron

C. Ipecac

D. Dronabinol

A

D. Dronabinol

27
Q

Which of the following is a 5-HT3 receptor antagonist used to reduce nausea and vomiting?

A. Scopolamine

B. Ondansteron

C. Ipecac

D. Dronabinol

A

B. Ondansteron (Zofran)

Integrated Biomedical Sciences (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions