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Step 1 > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

side effects of ethosuximide

A 
Ethosuximide
Fatigue
GI distress
Headache
Itching
stevens-Johnson syndrome
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2
Q

side effects of benzodiazapines

A

sedation, tolerance, dependence, respiratory depression

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3
Q

side effects of phenobarbital

A

sedation, tolerance, dependence, P450 induction, cardiorespiratory depression

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4
Q

side effects of phenytoin

A

nystagmus, diplopia, ataxia, sedation, peripheral neuropathy
hirsuitism, steven-Johnson syndrome, gingival hyperplasia, DRESS syndrome
osteopenia, SLE like syndrome
megaloblastic anaemia,
teratogenic - fetal hydanton syndrome
P450 induction

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5
Q

side effects of carbamazepine

A

diplopia, ataxia, agranulocytosis, aplastic anaemia, liver toxicity, teratogenic, induced P450, SIADH, Stevens-Johnson syndrome

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6
Q

side effects of valproic acid

A

GI distress, hepatotoxicity (fatal), pancreatitis, neural tube defects, weight gain

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7
Q

side effects of gabapentin

A

sedation, ataxia

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8
Q

side effects of topiramate

A

sedation, mental dulling, kidney stones, weight loss, acute closed angle glaucoma

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9
Q

side effects of lamotrigine

A

Stevens-Johnson syndrome

titrate slowly to reduce the risk

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10
Q

side effects of vigabatrin

A

concentric visual field loss

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11
Q

Don’t give X with morphine

A

butorphanol (partial agonist)

causes withdrawl

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12
Q

Don’t give X with naloxone

A

pentazocine (antagonist)

causes withdrawl

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13
Q

succinylcholine

A

ACh agonist

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14
Q

stigmines

A

anticholinesterase inhibitors - increase ACh in the synapse

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15
Q

Curiums

A

ACh competitive antagonists

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16
Q

pramiprexole, ropinirole, bromocriptine

A

DA agonists

17
Q

amantadine

A

increases DA release

18
Q

entacapone

A

prevents peripheral L-dopa degredation

19
Q

seleginine

A

inhibits MAO-B

stops DA breakdown

20
Q

tolcapone

A

inhibits CMOT

blocks DA conversion

21
Q

Benztropine

A

for tremor and rigidity

antimuscarinic

22
Q

memantine

A

Alzheimers

NMDA R antagonist

23
Q

Donepezil, galantamine, tacrine

A

Alzheimers

AChE inhibitors

24
Q

Tetrabenazine, reserpine

A

Huntingdon’s

inhibit VMAT - decrease DA

25
Q

Riluzole

A

ALS

decreases glutamate exitotoxicity

26
Q

Triptans

A

5-HT agonists

Step 1 (18 decks)

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