Pharmacology 4 - Common CV Drugs (I:2 done)

Question 1

What drugs can be used to treat hypertension? (6)

Answer 1

Alpha blockersACEIARBBeta blockersCalcium channel antagonistsThiazide like diuretic

Question 2

What do all beta blockers end in?

Answer 2

-olol

Question 3

What do ACEI end in?

Answer 3

-pril

Question 4

What do all ARB end in?

Answer 4

-artan

Question 5

What drugs can be used to treat angina? (6)

Answer 5

Beta blockersCalcium antagonistsNitratesNicorandilIvabradineRanolazine

Question 6

What are the 3 categories of anti-thrombotic drugs?

Answer 6

Anti-Platelet drugsAnti-coagulantsFibrinolytics

Question 7

What are 4 examples of anti-platlet drugs?

Answer 7

AspirinClopidogrelPrasugrelTicagrelor

Question 8

What are 3 examples of anti-coagulant drugs?

Answer 8

WarfarinRivaroxabanDabigatran

Question 9

What are 2 examples of fibrinolytic drugs?

Answer 9

StreptokinaseTissue Plasminogen activator (tPA)

Question 10

What are 2 groups of anti-cholesterol drugs?

Answer 10

StatinsFibrates

Question 11

What are the 5 main groups of CV drugs?

Answer 11

Anti-hypertensivesAnti-anginalsAnti-thromboticAnti-cholesterolAnti-arrhythmics(+others)

Question 12

How do diuretics work?

Answer 12

They block Na reabsorption in the kidneys and reduce the amount of fluid in the body

Question 13

What are the 2 categories of diuretics?

Answer 13

Thiazide like diuretics (mild)Loop diuretics (stronger)

Question 14

Example of a thiazide like diuretic?Used to treat?

Answer 14

BendrofluazideHypertension

Question 15

Example of a loop diuretic?Used to treat?

Answer 15

FurosemideHeart failure

Question 16

Side effects of diuretics? (4)

Answer 16

Hypokalaemia (tired, arrhythmias)HyperglycaemiaIncreased uric acid = goutImpotence

Question 17

How do beta blockers work?

Answer 17

They block beta 1 +/- beta 2 adrenoceptors

Question 18

What is an example of a cardioselective beta blocker?What is this used to treat? (3)

Answer 18

AtenololAnginaHypertensionHeart failure

Question 19

What is an example of a non selective beta blocker?What is it used to treat?

Answer 19

PropranololThyrotoxicosis

Question 20

Contra-indication for use of beta blocker?

Answer 20

Asthma

Question 21

Side effects of beta blockers?

Answer 21

AsthmaTirednessHeart failure (good in the long term but can worsen it in the short term)Cold peripheries

Question 22

2 types of calcium antagonists?

Answer 22

DihydropyridinesRate limiting calcium antagonists

Question 23

Example of a dihydropyridine?What is used to treat? (2)Side effects?

Answer 23

AmlodipineHypertension and anginaAnkle oedema

Question 24

2 examples of rate limiting calcium antagonists?What are they used to treat?What should these never be used with?

Answer 24

Verapamil, DilitiazemHypertension, angina, SV arrhythmiasBeta blockers

Question 25

How do alpha blockers work?

Answer 25

Block alpha adrenoceptos to cause vasodialtion

Question 26

What are alpha blockers used to treat?

Answer 26

hypertensionProstatic hypertrophy

Question 27

Example of alpha blocker?Side effects?

Answer 27

DoxazosinPostural hypotension

Question 28

How do ACEI work?

Answer 28

Block angiotensin I from becoming angiotensin II

Question 29

Example of an ACEI?

Answer 29

Lisinopril

Question 30

What are ACEI used for?

Answer 30

Hypertension and heart failure

Question 31

In terms of the kidneys what is ACEI good and bad for?

Answer 31

Good for diabetic nephropathyBad for renal artery stenosis