Pharmacokinetics Properties Of Drug Flashcards
What is the drug journey through oral route
What are important characteristics for a drug
Why are amines good functional group
Capillaries are the home where what
Oxygen, nutrients and drugs escape from blood to tissue and organs
Human body has how many capillaries
10 billions capillaries cover total surface area of 200 m2
Capillaries are made of what
Thin single layer of cells with pores in between
Can plasma proteins escape through the pores
No, the pores are large enough for most drugs to escape but too small for plasma proteins to escape
Where and when the drug will end up depends on what
What are some barriers
What are metabolites
What is the main metabolizing organ in the body
Liver, however metabolism can occur also in intestine, blood and some organs
What is responsible for the metabolism of a majority of small-molecule
Cytochrome p450
Explain excretion
Elimination covers what ?
What is the lipinskis rule of 5
