Antihistamine Part 2

Question 1

Explain the two groups of H1 antagonists

Answer 1

Question 2

What are the clinical uses of H1 antagonists

Answer 2

Question 3

What are other clinic? uses of H1 antagonists

Answer 3

Question 4

What are the common structural features of classical antihistamines

Answer 4

Question 5

1st Generation antihistamines chemically are classified into what

Answer 5

Question 6

What is the prototype of ethanolamine ethers

Answer 6

Diphendryamine

Question 7

What significant effects does ethanolamine ethers have

Answer 7

Question 8

What is the importance of alkyl substitution at the C2 or C4 position

Answer 8

Question 9

What is diphenhydramine and what does it relieve

Answer 9

Question 10

What are the side effects of diphenhydramine

Answer 10

Question 11

Can Diphenhydramine cross BBB

Answer 11

Question 12

Diphenhydramine is used in treatment of what

Answer 12

Question 13

Explain the metabolism of diphenhydramine

Answer 13

Question 14

What is the difference between Alkyl amines and diphenhydramine

Answer 14

Question 15

What will be the effect of adding halogen (Cl) to alkyl amines

Answer 15

Question 16

Metabolism of alkyl amines is primarily by what

Answer 16

Question 17

What are the famous members of alkyl amines

Answer 17

Question 18

Are alkyl amines OTC

Answer 18

Question 19

Which enantiomer in alkyl amines have greater affinity

Answer 19

S

Question 20

What is the most selective H1 antagonists 1st generation

Answer 20

Alkyl amines

Question 21

Piperazines are structurally related to what

Answer 21

Question 22

What is the structure of piperazines

Answer 22

Question 23

Piperazines used for what

Answer 23

Question 24

Piperazines have what activities

Answer 24

Question 25

Explain cetirizine

Answer 25

Question 26

Give example of tricyclic antihistamines

Answer 26

Phenothiazines

Question 27

What is the structure of phenothiazines

Answer 27

Question 28

What is the effect and use of phenothiazines

Answer 28

Question 29

Second generation antihistamines where produced for what goal

Answer 29

Question 30

Examples of second generation antihistamines

Answer 30

Question 31

Explain 2nd generation non sedating antihistamines

Answer 31

Question 32

Explain fexofenadine and terfenadine

Answer 32

Question 33

Explain loratadine and desloratadine

Answer 33

Question 34

Explain cetirizine

Answer 34

Question 35

Antihistamines that produce sedation can do what

Answer 35

Question 36

Antihistamines that possess anticholinergic actions can produce what

Answer 36

Question 37

Explain terfenadine interaction

Answer 37