Pharmacodynamics

Question 0

(2006)

Define tachyphylaxis. What is the significance of tachyphylaxis in drugs in anaesthesia?

Answer 0

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Question 1

(2011)

Explain and discuss the receptor theories. Illustrate with appropriate examples of each type.

Answer 1

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Question 2

(2004)

Explain the terms summation, antagonism, potential ion and synergism, giving an example for each.

Answer 2

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Question 3

(2000/02)
Define agonist, partial agonist, reversible competitive antagonist. Illustrate on drug response curves and give an example of each.

Answer 3

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Question 4

(2000)

Using drug examples of each, explain what is meant by 1st order and zero order kinetics.

Answer 4

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Question 5

(2000)

List the principles by which drug action is terminated, giving examples for each.

Answer 5

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Question 6

(Additional)

Discuss the possible interactions that can occur between agents.

Answer 6

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Question 7

(Additional)

What is pharmacological synergy? Give examples encountered in anaesthetic practice.

Answer 7

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