Neuromuscular Blocking Agents

Question 0

(2011)

Outline the factors that affect the reversal of various groups of non-depolarizing muscle relaxants.

Answer 0

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Question 1

(2012)
Describe the structure of the nicotinic acetylcholine receptor (nACh). How do neuromuscular blocking drugs interact with this receptor to cause paralysis?

Answer 1

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Question 2

(2009)

Describe the factors that may decrease the clinical response to non-depolarizing neuromuscular blocking agents.

Answer 2

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Question 3

(2009)

What is rocuronium? Describe the advantages and disadvantages of using rocuronium for rapid sequence induction.

Answer 3

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Question 4

(2001/09)
Outline the factors that determine the onset of neuromuscular block. Compare suxamethonium with rocuronium in regard to this.

Answer 4

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Question 5

(2007)
Describe the structure of rocuronium and its metabolism and elimination. What is the theory behind its relatively fast onset of action?

Answer 5

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Question 6

(2006)

Briefly describe the factors that determine the speed of onset of neuromuscular blocking agents.

Answer 6

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Question 7

(2005)

Write a brief outline of factors that may prolong duration of action of non-depolarizing muscle relaxants.

Answer 7

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Question 8

(2004)
Draw a diagram of neuromuscular junction and an acetylcholine receptor. Explain briefly the mechanism of action of depolarizing and non-depolarizing neuromuscular blocking drugs.

Answer 8

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Question 9

(2002)

Describe briefly the actions of suxamethonium and its metabolism. Outline factors which prolong the duration of action.

Answer 9

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Question 10

(Additional)

Outline the factors that increase action of neuromuscular blockers.

Answer 10

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