Pharmacodynamics Flashcards
High abuse potential, no medical use are considered …
Schedule 1 drugs (Ex: Heroine)
high abuse potential; accepted medical use
Schedule 2 drugs (Ex: Morphine)
low to moderate dependecne;m low amounts of opioids
Schedule 3 (Ex: Codeine)
low abuse potential; rx needed
Schedule 4 (Ex: Valium)
low abuse; may have small amounts of controlled substances
Schedule 5 (ex: Lomotril)
It is ok to leave medications at bedside. T or F
FALSE
How do herbs affect prescription meds?
It can increase or decrease the effect of drugs
Grapefruit is a herb that affects many medications. T or F
True
a drug that has been tested but not financially viable
orphan drug
study of the interactions between living systems & the foreign chemicals (drugs)
Pharmacodynamics
4 ways in which drugs work
-Replace or substitute missing chemicals
-Increase or stimulate certain cellular activities
-Depress or slow cellular activities
-Interfere with the functioning of foreign cells, such as invading microorganisms or neoplasms that cause cell death
concentration a drug must reach in the tissues/blood for it to work
Drug Potency/Critical Concentration
a higher dose than is usually used for treatment, allowing the drug to reach the critical concentration sooner
Loading Dose
a ratio of the blood concentration at which a drug becomes toxic to the concentration at which the drug is effective
Therapeutic Index
The larger the therapeutic index, the safer the drug is. T or F
True
the time it takes for the amount of a drug’s active substance in your body to reduce by half
half life
highest amount of drug in blood
lowest amount of drug in blood
peak level
trough level
Vancomycin requires peak and trough tests before re-administered. T or F
True
drug that binds to a receptor in body and activates it
agonist
drug that binds to receptor in body and blocks the effect it should produce
antagonist aka antidotes
drugs that are more powerful when given in combination
synergistic
specific areas on cell membranes that react with certain chemicals to cause an effect within the cell.
receptor sites
harms the target/microbe w/o causing harm to host
selective toxicity
