PHARMACODYNAMICS Flashcards
the study of the biochemical and physiologic effects of drugs on the body and the molecular mechanisms by which those effects are produced.
Pharmacodynamics
is the study of what drugs do to the body and how they do it.
Pharmacodynamics
largest effect that a drug can produce.
Maximal Efficacy
amount of drug we must give to elicit an effect.
Relative Potency
Functional macromolecule in a cell to which a drug binds to produce its effects.
Drug Receptors
the term affinity refers to the strength of the attraction between a drug and its receptor.
Affinity.
refers to the ability of a drug to activate a receptor upon binding.
Intrinsic Activity
is an agonist that has only moderate intrinsic activity
Partial Agonists
is a measure of a drug’s safety.
THE THERAPEUTIC INDEX