kintics Flashcards

1
Q

is the study of drug movement throughout the body.

A

pharmacokinetics

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2
Q

movement of a drug from its site of administration into the blood.

A

Absorption

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3
Q

in which a drug gets metabolized at a specific location in the body that results in a reduced concentration of the active drug upon reaching its site of action or the systemic circulation.

A

The first pass effect

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4
Q

drug movement from the blood to the interstitial space of tissues and from there into cells.

A

Distribution

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5
Q

Drug distribution is determined by three major factors:

A

blood flow to tissues,
the ability of a drug to exit the vascular system, the ability of a drug to enter cells.

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6
Q

The rate at which drugs are delivered to a particular tissue is determined by?

A

by blood flow to that tissue.

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7
Q

also known as biotransformation, is defined as the chemical alteration of drug structure.

A

Drug metabolism

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8
Q

increase rates of drug metabolism are

A

inducers

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9
Q

decrease rates of drug metabolism

A

inhibitors

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10
Q

removal of drugs from the body.

A

EXCRETION

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11
Q

the time required for the amount of drug in the body to decrease by 50%.

A

Drug half-life

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