DIURETICS Flashcards
give example of Loop Diuretics
Furosemide, Ethacrynic acid
What is the side effect of Loop Diuretics?
Hypokalemic, metabolic alkalosis
Hypomagnesemia
Ototoxicity
Hyperuricemia
What is the side effect of Thiazide Diuretics?
• Hyponatremia
• Hypokalemic,
Metabolic Alkalosis
• Hypercalcemia
• Hyperuricemia
• Hyperglycemia
• Hyperlipidemia
What is the uses of Potassium-Sparing Diuretics?
- To prevent Hypokalemia caused by other diuretics
- Hyperaldosteronism (aldosterone antagonists, e.g. spironolactone)
The side effect of Potassium-Sparing Diuretics?
Hyperkalemia
What is the Spironolactone-specific (anti-adrenergic) effects?
Ø - Gynecomastia & impotence (males)
Ø - Menstrual irregularities (females)
What the uses of Carbonic anhydrase inhibitors?
1-Open angle glaucoma
2-Oedema with Metabolic Alkalosis
3-Acute Mountain sickness
What is the side effect of Carbonic anhydrase inhibitors?
• HYPOkalemic Metabolic Acidosis
• Renal calcium stones (due to urine alkalinization) • Paresthesia
What is the uses of Osmotic Diuretics?
- Raised Intracranial pressure in neurologic condition (e.g. cerebral edema)
- Raised Intraocular pressure in acute glaucoma
What is the side effect of Osmotic Diuretics?
• Extracellular Volume Expansion (e.g. pulmonary oedema)
• Dehydration
Potassium-Sparing Diuretics(Side Effect)
Hyperkalemia