Drugs used in epilepsy Flashcards
1st Generation Drugs?
Phenytoin
Carbamazepine
Ethosuximide
Sodium valproate
Drug of choice in Absence seizure?
Ethosuximide
2nd Generation Drugs?
Lamotrigine
Topiramate
Levetiracetam
Uses of Phenytoin?
• Status epilepticus
• partial and generalized tonic-clonic seizures
Gum Hyperplaia
Phenytoin
Drug of choice in partial seizures
Carbamazepine
Enzyme inhibitor?
Sodium valproate
Side effects Sodium valproate?
• Thrombocytopenia
• Hepatotoxicity
• Weight gain
• teratogenicity (highest risk
Lower risk for teratogenicity.
Lamotrigine
Side effects Lamotrigine?
Steven –
Johnson syndrome
Side effects Topiramate?
Weight loss
Side effects Levetiracetam?
Negative psychotropic effect (mood
disorder, irritability, aggressiveness)
Lower potential for drug interaction
(no action on liver enzymes)
Levetiracetam
Lower potential for drug interaction
(no action on liver enzymes)
Levetiracetam