Drugs used in epilepsy Flashcards

1
Q

1st Generation Drugs?

A

Phenytoin

Carbamazepine

Ethosuximide

Sodium valproate

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2
Q

Drug of choice in Absence seizure?

A

Ethosuximide

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3
Q

2nd Generation Drugs?

A

Lamotrigine

Topiramate

Levetiracetam

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4
Q

Uses of Phenytoin?

A

• Status epilepticus
• partial and generalized tonic-clonic seizures

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5
Q

Gum Hyperplaia

A

Phenytoin

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6
Q

Drug of choice in partial seizures

A

Carbamazepine

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7
Q

Enzyme inhibitor?

A

Sodium valproate

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8
Q

Side effects Sodium valproate?

A

• Thrombocytopenia
• Hepatotoxicity
• Weight gain
• teratogenicity (highest risk

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9
Q

Lower risk for teratogenicity.

A

Lamotrigine

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10
Q

Side effects Lamotrigine?

A

Steven –
Johnson syndrome

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11
Q

Side effects Topiramate?

A

Weight loss

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12
Q

Side effects Levetiracetam?

A

Negative psychotropic effect (mood
disorder, irritability, aggressiveness)

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13
Q

Lower potential for drug interaction
(no action on liver enzymes)

A

Levetiracetam

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14
Q

Lower potential for drug interaction
(no action on liver enzymes)

A

Levetiracetam

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