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Pharmacology > COAGULATION DRUGS > Flashcards

COAGULATION DRUGS Flashcards

1
Q

What is the Antidote of Unfractionated Heparin (UFH)?

A

Protamine Sulfate

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2
Q

Side effects of Unfractionated Heparin (UFH)?

A

Heparin-induced thrombocytopenia (HIT) → abnormal platelet activation & hypercoagulation v Long-term heparin therapy is associated with osteoporosis

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3
Q

Use of Unfractionated Heparin (UFH)?

A

Prevention of coagulation during renal dialysis

Prevention of DVT

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4
Q

Indirect Parenteral Anticoagulants (Heparins)

A

Enoxaparin

Fondaparinux

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5
Q

Parenteral Direct Thrombin Inhibitors

A

Argatroban

Bivalirudin

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6
Q

Oral Direct Factor Xa Inhibitors

A

Rivaroxaban

Apixaban

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7
Q

Side effects of Warfarin?

A

v Bleeding
v Cutaneous necrosis

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8
Q

Uses of Warfarin?

A

valvular heart disease / prosthetic valves

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9
Q

Thromboxane Inhibitor

A

Thromboxane Inhibitor

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10
Q

Thrombolytics

A

Streptokinase

Alteplase

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11
Q

antidote to thrombolytic therapy?

A

Aminocaproic acid

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Pharmacology (19 decks)

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