COAGULATION DRUGS

Question 1

What is the Antidote of Unfractionated Heparin (UFH)?

Answer 1

Protamine Sulfate

Question 2

Side effects of Unfractionated Heparin (UFH)?

Answer 2

Heparin-induced thrombocytopenia (HIT) → abnormal platelet activation & hypercoagulation v Long-term heparin therapy is associated with osteoporosis

Question 3

Use of Unfractionated Heparin (UFH)?

Answer 3

Prevention of coagulation during renal dialysis

Prevention of DVT

Question 4

Indirect Parenteral Anticoagulants (Heparins)

Answer 4

Enoxaparin

Fondaparinux

Question 5

Parenteral Direct Thrombin Inhibitors

Answer 5

Argatroban

Bivalirudin

Question 6

Oral Direct Factor Xa Inhibitors

Answer 6

Rivaroxaban

Apixaban

Question 7

Side effects of Warfarin?

Answer 7

v Bleeding
v Cutaneous necrosis

Question 8

Uses of Warfarin?

Answer 8

valvular heart disease / prosthetic valves

Question 9

Thromboxane Inhibitor

Answer 9

Thromboxane Inhibitor

Question 10

Thrombolytics

Answer 10

Streptokinase

Alteplase

Question 11

antidote to thrombolytic therapy?

Answer 11

Aminocaproic acid