Pharm objectives 4 Flashcards

1
Q

What is the biggest risk associated with benzodiazepines?

A

High dependency can develop during and after treatment.

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2
Q

What is a major side effect of first-Generation antipsychotic medications?

A

Neuroleptic Malignant Syndrome, Sedation, Parkinsonism, Akathisia ,Tardive dyskinesia

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3
Q

Tardive dyskinesia?

A

Twitching of the mouth, tongue, lips and occasionally the limbs.

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4
Q

Neuroleptic malignant syndrome?

A

Sudden high fever, blood pressure, tachycardia and
cardiac rhythm changes and Life threatening

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5
Q

How do we treat these side effects of first-Generation antipsychotic medications?

A

Treat with anticholinergic agents such as benztropine

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6
Q

Common medications used to prevent seizures?

A

Antiepileptics medication

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7
Q

What medication is used to stop seizures?

A

Benzodiazepines such as Diazepam, Lorazepam, Chlordiazepoxide, Clorazepate,
Oxazepam, Clonazepam

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8
Q

Uses for lorazepam?

A

Stop seizure, Muscle relaxer, anxiety, panic disorder

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9
Q

What are the side effects of lithium toxicity?

A

GI distress, fine/coarse tremors, mental status changes, sedation, coma and/or death

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10
Q

lithium toxicity levels?

A

Above 1.5 lithium

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11
Q

What is the major difference between a SNRI and an SSRI?

A

SSRIs they only impact the amount of serotonin in your body.
SNRIs, they impact both serotonin and norepinephrine

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12
Q

SSRI medications

A

Fluoxetine, Sertraline, Citalopram, Escitalopram, Paroxetine

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13
Q

.Why are non-barbiturates preferred by healthcare providers?

A

Dependency is less likely, does not result in sedation or potential CNS depressants, less side effects.

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14
Q

What is serotonin syndrome?

A

Can begin 2 -72hr, having too much serotonin

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15
Q

Name the medications that can cause serotonin syndrome?

A

SSRI, SNRI

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16
Q

What medication causes an elevated level of tyramine?

A

MAOIs

17
Q

What is an important education topic for patients who take these MOIs?

A

MAOI’s increase the amount of tyramine in the body, which can in turn cause elevated blood pressure. Educate on Tyramine-rich foods.

18
Q

Tyramine-rich foods?

A

Aged cheese, pepperoni, salami, avocados, figs, bananas, smoked fish, protein, soups, soy sauce, some beers, red wine

19
Q

What common mood stabilizer requires blood testing for therapeutic levels?

A

Lithium

20
Q

What name 2 disorders that are treated with lamotrigine?

A

Bipolar manic and depressive episodes

21
Q

What medication would you administer to a patient with glaucoma?

A

Beta Adrenergic Blocker, Alpha adrenergic agonists, Prostaglandin analogs, Cholinergic agonist, Carbonic anhydrase inhibitors.

22
Q

What’s the primary goal of therapy for glaucoma?

A

Reduce the pressure which in turn, preserves eyesight.

23
Q

Parkinson’s disease is related to a decrease in ___________ in the CNS

A

dopamine

24
Q

Medications that produce a DRY side effects

A

Tricyclic antidepressants, Antipsychotics 1-2nd generation.

25
Q

What specific side effects are DRY

A

Cant see (Blurred vision)
Cant pee (Urinary retention)
Cant spit (Dry mouth)
Cant shit (Constipation)
Tachycardia

26
Q

Medication that produces MOIST side effects

A

Cholinesterase Inhibitors:
Donepezil & Neostigmine

27
Q

What specific side effects are MOIST

A

Increased salivation, diarrhea, nausea, sweating ,Urinary incontinence

28
Q

Alzheimer’s disease?

A

Alzheimer disease—type of
dementia with amyloid plaques and tangled nerve bundles which
slow or block transmission within the brain

29
Q

Medication that is used to treat Alzheimer’s disease.

A

Donepezil & Neostigmine

30
Q

Parkinson disease?

A

Degenerative disorder
caused by an imbalance of dopamine and
acetylcholine in the CNS

31
Q

Parkinsonism symptoms

A

fine tremors, slowing of
voluntary movements, muscular
weakness

32
Q

Anti-parkinsons Drugs

A

levodopa/carbidopa,
Ropinirole, Selegiline

33
Q

3 muscle relaxants

A

Diazepam
Baclofen
Cyclobenzaprine