Pharm-Hematologic Flashcards
Cyanocobalamin- Vit B12- Indications
Deficiency due to dietary intake, alcohol abuse, GI surgery, absortion disorders
Cyanocobalamin- Vit B12- SE
HA, N/V, non-toxic even in large doses
Erythropoietin/darbapoetin- Indications
Anemia associated with HIV, cancer, end stage renal disease
Erythropoietin/darbapoetin-SE
Elevated BP, arthalgia, CV events, tumor progression
Folic acid- Indications
Anemia due to deficiency- pregnancy, estrogen, alcohol
Folic acid- SE
None, rarely hypersensitive rxn if injected
Ferrous sulfate- Indication
Iron deficiency anemia, blood loss,
Ferrous sulfate- SE
GI disturbances, dark stool
Methotrexate- Indications
ALL, Burkitt, meningeal leukemia
Methotrexate- AE
Category X, alopecia, erythema, rash renal failure, pulm toxicity
IV Iron- Indications
Chemo-assocaite anemia
IV Iron- SE
Hypersensitivity, hypotension
Steroids- Indications
ALL, CLL, CML, Multiple myeloma, Non-hodgkin- Part of R CHOP
Steroids- SE
Immunosupression, skin thinning, cataracts, HPA axis suppression